<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="research-article"><front><journal-meta><journal-id journal-id-type="nlm-ta">JMIR Serious Games</journal-id><journal-id journal-id-type="publisher-id">games</journal-id><journal-id journal-id-type="index">15</journal-id><journal-title>JMIR Serious Games</journal-title><abbrev-journal-title>JMIR Serious Games</abbrev-journal-title><issn pub-type="epub">2291-9279</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v13i1e73221</article-id><article-id pub-id-type="doi">10.2196/73221</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Paper</subject></subj-group></article-categories><title-group><article-title>The Impact of Active Augmented Reality Games on Physical Activity and Cognition Among Older Adults: Feasibility Study</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name name-style="western"><surname>Lu</surname><given-names>Amy Shirong</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Parkar</surname><given-names>Bhagyashree</given-names></name><degrees>MS</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Gupta</surname><given-names>Shiveshchandra</given-names></name><degrees>MS, MD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Hall</surname><given-names>Sierra</given-names></name><degrees>MPH, ALM</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Pindus</surname><given-names>Dominika M</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Kramer</surname><given-names>Arthur F</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff3">3</xref></contrib></contrib-group><aff id="aff1"><institution>Health Technology Lab, Department of Communication Studies, College of Arts, Media, and Design, Department of Public Health Science and Health Sciences, Bouv&#x00E9; College of Health Sciences, Northeastern University</institution><addr-line>360 Huntington Ave 212A Lake Hall</addr-line><addr-line>Boston</addr-line><addr-line>MA</addr-line><country>United States</country></aff><aff id="aff2"><institution>Department of Kinesiology and Community Health, Institute of Applied Life Sciences, University of Massachusetts Amherst</institution><addr-line>Amherst</addr-line><addr-line>MA</addr-line><country>United States</country></aff><aff id="aff3"><institution>Beckman Institute for Advanced Science and Technology, University of Illinois</institution><addr-line>Urbana</addr-line><addr-line>IL</addr-line><country>United States</country></aff><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Coristine</surname><given-names>Andrew</given-names></name></contrib></contrib-group><contrib-group><contrib contrib-type="reviewer"><name name-style="western"><surname>Bhowmick</surname><given-names>Pallabi</given-names></name></contrib></contrib-group><author-notes><corresp>Correspondence to Amy Shirong Lu, PhD, Health Technology Lab, Department of Communication Studies, College of Arts, Media, and Design, Department of Public Health Science and Health Sciences, Bouv&#x00E9; College of Health Sciences, Northeastern University, 360 Huntington Ave 212A Lake Hall, Boston, MA, 02115, United States, 1 6173737839; <email>a.lu@northeastern.edu</email></corresp></author-notes><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>3</day><month>10</month><year>2025</year></pub-date><volume>13</volume><elocation-id>e73221</elocation-id><history><date date-type="received"><day>27</day><month>02</month><year>2025</year></date><date date-type="rev-recd"><day>21</day><month>08</month><year>2025</year></date><date date-type="accepted"><day>25</day><month>08</month><year>2025</year></date></history><copyright-statement>&#x00A9; Amy Shirong Lu, Bhagyashree Parkar, Shiveshchandra Gupta, Sierra Hall, Dominika M Pindus, Arthur F Kramer. Originally published in JMIR Serious Games (<ext-link ext-link-type="uri" xlink:href="https://games.jmir.org">https://games.jmir.org</ext-link>), 3.10.2025. </copyright-statement><copyright-year>2025</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Serious Games, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://games.jmir.org">https://games.jmir.org</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://games.jmir.org/2025/1/e73221"/><abstract><sec><title>Background</title><p>Physical activity (PA) enhances physical health as well as cognitive and brain health, yet motivating older adults to initiate and sustain PA remains challenging, a difficulty exacerbated by the COVID-19 pandemic. Active augmented reality (AAR) games, integrating digital gameplay with real-world physical movement, provide an enjoyable and accessible means for PA promotion among older adults in independent living environments, mitigating barriers such as poor weather and unfavorable neighborhood environments. However, limited research has explored the feasibility and impact of AAR interventions in this population.</p></sec><sec><title>Objective</title><p>This feasibility study examines the acceptability, safety, and preliminary effects of AAR games to enhance PA levels and cognitive functions among older adults, as well as their user experiences. We also examined the practicality of home-based AAR gameplay using minimal equipment and constrained physical space.</p></sec><sec sec-type="methods"><title>Methods</title><p>Sixteen independent-living older adults aged 65&#x2010;85 years (mean 74.6, SD 3.73) participated in a single-session AAR intervention using the <italic>Active Arcade</italic> game set by playing four 10-minute AAR games. PA levels were assessed using ActiGraph wGT3x-bt accelerometers and Polar H10 heart rate monitors. Cognitive function was evaluated pre- and post-gameplay using NIH Toolbox&#x2019;s visual reasoning test and Flanker inhibitory control and attention tests. Surveys of PA intention and motivation as well as the gaming experience questionnaire, along with semistructured interviews, were conducted afterwards, providing both quantitative and qualitative insights into the feasibility and appeal of AAR gameplay from the target population.</p></sec><sec sec-type="results"><title>Results</title><p>All participants completed the study protocol without adverse events, demonstrating high feasibility and acceptability. Participants engaged in moderate-to-vigorous PA during 20%&#x2010;30% of the gameplay, as measured by accelerometers and heart rate monitors. Of the 16 participants, 7 were taking beta blockers. The mean values of average %HRMax suggest that those not on beta blockers generally met the moderate-intensity threshold, whereas those on beta blockers tended to fall slightly below it. Cognitive assessments revealed significant improvements in visual reasoning postintervention, with the effect sustained after adjustment for age and education (<italic>P</italic>=.03), suggesting potential cognitive benefits from a single bout of AAR gameplay. Survey responses indicated high levels of PA intention (mean 4.15/5, SD 0.59), motivation (mean 5.67/7, SD 1.24), high positive affect (mean 4.35/5, SD 0.80), and low negative affect (mean 1.30/5, SD 0.46) associated with AAR gameplay. Around 75% of gameplay occurred within a 4&#x00D7;4 ft area (mean 29.77/40 min, SD 2.46), indicating suitability for home environments. Thematically analyzed interview feedback emphasized participants&#x2019; enjoyment, ease of use, desire for progressive difficulty, and the need to cater to diverse physical abilities and individual preferences.</p></sec><sec sec-type="conclusions"><title>Conclusions</title><p>AAR games are a feasible, accessible, and enjoyable alternative for PA and cognitive engagement among older adults. Future research should investigate the long-term effects, sustainability, and broader applicability of AAR interventions to fully realize their potential in aging populations.</p></sec></abstract><kwd-group><kwd>active augmented reality</kwd><kwd>physical activity</kwd><kwd>active video games</kwd><kwd>cognitive function</kwd><kwd>older adults</kwd><kwd>feasibility study</kwd><kwd>health technology</kwd><kwd>AAR</kwd><kwd>PA</kwd><kwd>AVG</kwd></kwd-group></article-meta></front><body><sec id="s1" sec-type="intro"><title>Introduction</title><p>More than one-fifth of the US residents will be over the age of 65 years by 2030 [<xref ref-type="bibr" rid="ref1">1</xref>]. This significant demographic shift will increase both the relative and absolute number of older adults, presenting challenges across various aspects of health [<xref ref-type="bibr" rid="ref2">2</xref>]. Physical activity (PA) levels decrease significantly with age [<xref ref-type="bibr" rid="ref3">3</xref>,<xref ref-type="bibr" rid="ref4">4</xref>], and low PA is associated with numerous adverse outcomes such as high blood pressure, frailty, increased fall risk, depression, and cognitive decline [<xref ref-type="bibr" rid="ref5">5</xref>-<xref ref-type="bibr" rid="ref7">7</xref>]. Maintaining PA levels and cognitive function is pivotal for functional independence, effective communication, and overall quality of life [<xref ref-type="bibr" rid="ref8">8</xref>-<xref ref-type="bibr" rid="ref10">10</xref>]. There is a close connection between the cognitive well-being and older adults&#x2019; ability to manage daily tasks, with cognitive decline significantly impairing their ability for independent living [<xref ref-type="bibr" rid="ref11">11</xref>-<xref ref-type="bibr" rid="ref13">13</xref>].</p><p>According to the United Nations, one of the sustainable development goals is to ensure healthy lives and promote well-being for all ages [<xref ref-type="bibr" rid="ref14">14</xref>]. Moderate-to-vigorous PA (MVPA) is one of the most effective strategies to achieving these goals. It has been shown to decrease morbidity, prevent cognitive decline, and reduce the risk of mild cognitive impairment and Alzheimer disease and related dementias [<xref ref-type="bibr" rid="ref15">15</xref>-<xref ref-type="bibr" rid="ref18">18</xref>]. In fact, many forms of PA enhance physical, cognitive, and brain health and serve as a protective factor against future cognitive decline [<xref ref-type="bibr" rid="ref19">19</xref>,<xref ref-type="bibr" rid="ref20">20</xref>]. PA also improves cardiorespiratory fitness, reduces frailty and fall risk, and increases quality of life [<xref ref-type="bibr" rid="ref21">21</xref>-<xref ref-type="bibr" rid="ref23">23</xref>]. Additionally, PA has demonstrated an antidepressant effect in older adults, further contributing to their emotional and mental well-being [<xref ref-type="bibr" rid="ref24">24</xref>].</p><p>The World Health Organization recommends that adults, including older adults, engage in at least 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity PA per week [<xref ref-type="bibr" rid="ref25">25</xref>]. However, motivating older adults to initiate and sustain PA remains challenging, exacerbated by the COVID-19 pandemic, which has created additional barriers to PA [<xref ref-type="bibr" rid="ref26">26</xref>]. Even after the pandemic has passed, its negative impact on older adults persists, contributing to declines in PA levels, mobility, and overall well-being [<xref ref-type="bibr" rid="ref27">27</xref>]. Common obstacles include low motivation, limited access to facilities, fear of injury or falls, and a lack of knowledge about proper exercise techniques [<xref ref-type="bibr" rid="ref28">28</xref>]. Addressing these challenges is critical to providing older adults with opportunities to increase PA levels, promoting their physical and cognitive health while fostering overall well-being.</p><p>The American College of Sports Medicine has identified the integration of technology to achieve PA goals as &#x201C;the future of fitness,&#x201D; with exercise programs for older adults ranking third on their list of trends for 2025 [<xref ref-type="bibr" rid="ref29">29</xref>]. Active video games (AVG), or any video game that requires PA as part of gameplay, have the potential to overcome traditional barriers to PA for older adults. Extended reality technologies, including virtual reality (VR) and augmented reality (AR), have shown promise in promoting PA and enhancing cognitive functioning in older adults [<xref ref-type="bibr" rid="ref30">30</xref>]. Active augmented reality (AAR) games, a subset of AVG, leverage AR technologies to incorporate active gameplay. Unlike VR, AR integrates digital graphics and information into the user&#x2019;s physical environment, creating an immersive and interactive experience that blends the real and virtual worlds [<xref ref-type="bibr" rid="ref31">31</xref>].</p><p>AR technology has experienced rapid growth, with a projected market value exceeding US $635 billion by 2033 [<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref33">33</xref>]. In 2022, over 70% of Americans believed that AR would become an integral part of everyday life, with 89% viewing it as beneficial [<xref ref-type="bibr" rid="ref34">34</xref>]. Notably, the baby boomer generation has shown a surprising openness to exploring extended reality technologies. A 2023 survey revealed that 70% of baby boomers expressed interest in trying AR/VR technology, suggesting its potential for adoption among older adults [<xref ref-type="bibr" rid="ref35">35</xref>]. Indeed, older adults have demonstrated positive attitudes and high interest in AR [<xref ref-type="bibr" rid="ref36">36</xref>-<xref ref-type="bibr" rid="ref39">39</xref>]. Active AR, or AAR interventions, have been successfully implemented in older adults for various health-related purposes, including improving balance [<xref ref-type="bibr" rid="ref40">40</xref>] and reducing muscle loss [<xref ref-type="bibr" rid="ref41">41</xref>]. AAR has also been well received by those with Alzheimer disease and related dementias [<xref ref-type="bibr" rid="ref42">42</xref>] and Parkinson disease [<xref ref-type="bibr" rid="ref43">43</xref>], indicating its adaptability across different aging-related conditions.</p><p>AAR games integrate real-world movements to enhance physical coordination while keeping users engaged through interactive, immersive experiences. By combining physical exercise with cognitive challenges, AR-based game interventions provide a dual benefit, promoting both physical and cognitive health [<xref ref-type="bibr" rid="ref44">44</xref>]. While these initial findings are promising, there remains a significant gap in research on AAR&#x2019;s role in promoting PA and preventing cognitive decline. Understanding older adult usage of AAR is crucial for maximizing its potential as a health-promoting intervention.</p><p>AAR could serve as an effective, enjoyable, and accessible method for promoting PA motivation and adherence among older adults, mitigating traditional PA barriers such as poor weather and unsafe neighborhood environments. While older adults have historically been underrepresented in digital design, which partly contributes to their lower utilization of AR devices [<xref ref-type="bibr" rid="ref45">45</xref>], they have shown a growing enthusiasm for AR technologies [<xref ref-type="bibr" rid="ref33">33</xref>]. AAR games are increasingly gaining popularity as a means of engaging older adults in PA [<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref47">47</xref>]. Commercially available platforms, such as Nintendo Wii and Microsoft Kinect, have introduced AAR-based games that enable users to engage in interactive exercise experiments from the comfort of their homes. These systems offer games designed to accommodate varying levels of difficulty and skill, making them a versatile option for older adults seeking to integrate PA into their daily routines. Moreover, AR technology extends beyond physical exercise, contributing to the psychological and social well-being of older adults. Research indicates that AR applications create enjoyable and engaging experiences, which can enhance motivation and promote adherence to exercise routines [<xref ref-type="bibr" rid="ref30">30</xref>]. Additionally, the immersive nature of AR fosters mental engagement, helping older adults combat loneliness and social isolation [<xref ref-type="bibr" rid="ref30">30</xref>].</p><p>As AR technology continues to evolve, further research is needed to address existing challenges and investigate the long-term benefits of AR interventions on cognitive health and physical abilities in older adults. This feasibility study seeks to bridge this research gap by examining the positive effects of AR games on PA and cognition in older adults. The study employs a mixed-method design with pre- and postintervention assessments, integrating both quantitative and qualitative research methods to evaluate the impact of AAR games on PA levels and cognitive functioning in older adults. The following research questions (RQs) guide this investigation:</p><p>RQ1: Can AAR induce MVPA among older adults?</p><p>RQ2: Will AAR improve older adults&#x2019; PA intention?</p><p>RQ3: Can AAR improve cognitive outcomes among older adults?</p><p>RQ4: What are older adults&#x2019; cognitive and affective responses to the AAR gaming experience?</p></sec><sec id="s2" sec-type="methods"><title>Methods</title><sec id="s2-1"><title>Ethical Considerations</title><p>The Northeastern University Institutional Review Board approved the study (#23-09-28). All participants signed written informed consent. Each participant completed the protocol behind a closed door, and the study data were deidentified before being analyzed. Each participant received a US $100 gift card at the end of the study session.</p></sec><sec id="s2-2"><title>Sample</title><p>Participants were recruited through web advertisements and on-campus posters at the first author&#x2019;s institution. Additionally, potential participants were identified from the IGNITE (Investigating Gains in Neurocognition in an Intervention Trial of Exercise) [<xref ref-type="bibr" rid="ref48">48</xref>] trial database and contacted by phone. The inclusion criteria targeted adults aged 65&#x2010;85 years, ensuring an equal gender distribution, English language proficiency, absence of cognitive impairments, and sufficient physical ability to complete the study protocol (ie, without significant balance or mobility issues). More specifically, all participants completed a comprehensive neuropsychological evaluation, including the Montreal Cognitive Assessment, and all participants passed without being classified as cognitively impaired [<xref ref-type="bibr" rid="ref49">49</xref>]. Exclusion criteria included any history of acute or chronic physical, cognitive, or mental health conditions that could interfere with participation in exercise. Approval from participants&#x2019; primary care providers was also required. To control for potential bias, only individuals who had never played the AAR games selected for the study were invited to participate.</p><p>Approximately 160 individuals were contacted by phone, with 65 expressing interest in the study. Of these, 39 older adults underwent screening using the Physical Activity Readiness Questionnaire [<xref ref-type="bibr" rid="ref50">50</xref>] and the Late Life Function and Disability Screening Function and Disability Component [<xref ref-type="bibr" rid="ref51">51</xref>]. A total of 17 respondents passed the screening, and 16 participants were included in the study.</p></sec><sec id="s2-3"><title>AAR Game</title><p>For this project, we selected <italic>Active Arcade</italic> (Nex, San Jose, CA) as the AAR game set. As one of the newer AR-based AVGs, <italic>Active Arcade</italic> is powered by proprietary computer vision technology used in pro sports and is freely available on iOS [<xref ref-type="bibr" rid="ref52">52</xref>] and Android [<xref ref-type="bibr" rid="ref53">53</xref>] stores. <italic>Active Arcade</italic> tracks body movements via a smartphone or tablet camera, requiring no wearables. It offers full-body games playable solo or with others, making it accessible across age and fitness levels. Its simple setup suits home-based use. A 2022 Apple Design Award finalist, the app has logged over 100 million play sessions since its 2021 launch [<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref55">55</xref>]. It is compatible with smartphones and tablets on both major operating systems and can be displayed on any TV using an HDMI adapter [<xref ref-type="bibr" rid="ref55">55</xref>].</p></sec><sec id="s2-4"><title>General Procedures</title><p>Upon arrival, participants were provided with written informed consent before completing an online questionnaire (see <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>) to record demographic information. Research assistants (RAs) measured each participant&#x2019;s height using a stadiometer (ShorrBoard, Weight and Measure, LLC, Olney, MD) and weight with a calibrated scale (SECA 813, SECA Inc., Chino, CA). To ensure focus during the session, the RAs instructed participants to set their personal mobile devices to &#x201C;Do Not Disturb&#x201D; mode.</p><p>An accelerometer (wGT3x-bt; ActiGraph, Pensacola, FL) was attached to each participant&#x2019;s nondominant hip, and a heart rate (HR) band (Polar H10; Polar, Kempele, Finland) was secured to their chest. Baseline resting HR and rate of perceived exertion (RPE) were recorded using the Borg Category-Ratio (CR-10) [<xref ref-type="bibr" rid="ref56">56</xref>]. Participants then completed two cognitive tests from the NIH Toolbox, the visual reasoning test, and the Flanker inhibitory control and attention test, before receiving gameplay instructions from the RAs. The NIH Toolbox is a validated, standardized battery developed by the National Institutes of Health to measure neurological and behavioral function across the lifespan [<xref ref-type="bibr" rid="ref57">57</xref>]. For this study, we selected two specific tests because they target cognitive domains (fluid reasoning and executive function) that have shown associations with PA in older adults [<xref ref-type="bibr" rid="ref58">58</xref>,<xref ref-type="bibr" rid="ref59">59</xref>]. Visual reasoning assesses problem-solving and visuospatial skills, while the Flanker task measures attention and inhibitory control. Together, they offer a concise but meaningful assessment of the cognitive processes most likely to be influenced by interactive, movement-based AAR gameplay.</p><p>Participants engaged in four 10-minute <italic>Active Arcade</italic> AR mini-games, interspersed with rest intervals, while HR was continuously monitored. The games were randomly assigned in blocks with progressively increasing intensities. The <italic>Active Arcade</italic> game includes a variety of mini games; for this study, participants played <italic>Reaction Flow</italic> (<xref ref-type="fig" rid="figure1">Figure 1</xref>), <italic>Whack a Mole</italic> (<xref ref-type="fig" rid="figure2">Figure 2</xref>), and two modes of <italic>Super Hits</italic> [Catch (<xref ref-type="fig" rid="figure3">Figure 3</xref>) and Slash (<xref ref-type="fig" rid="figure4">Figure 4</xref>)], totaling 40 minutes of gameplay (10 min per game). We did not modify any part of the game, as the <italic>Active Arcade</italic> game set was designed for all ages and ability levels, with games accessible to both children and older adults. These four games, as well as their order of presentation, were pretested and selected by two additional older adults meeting the same inclusion criteria and by lab staff experienced in AVG research, using the same PA measurement protocol, to ensure that the level of difficulty increased progressively. The gameplay took place in a square-shaped space divided into inner (4&#x00D7;4 sq ft), middle (6&#x00D7;6 sq ft), and outer (8&#x00D7;8 sq ft) zones. Games began only when participants&#x2019; HR was within their resting HR range. After gameplay, participants repeated the NIH Toolbox cognitive tests to assess post-gameplay cognitive performance.</p><fig position="float" id="figure1"><label>Figure 1.</label><caption><p>Reaction Flow.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="games_v13i1e73221_fig01.png"/></fig><fig position="float" id="figure2"><label>Figure 2.</label><caption><p>Whack a Mole.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="games_v13i1e73221_fig02.png"/></fig><fig position="float" id="figure3"><label>Figure 3.</label><caption><p>Super Hits&#x2014;Catch.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="games_v13i1e73221_fig03.png"/></fig><fig position="float" id="figure4"><label>Figure 4.</label><caption><p>Super Hits&#x2014;Slash.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="games_v13i1e73221_fig04.png"/></fig><p>After gameplay, participants completed surveys assessing intentions, motivations, and gaming experience. The session concluded with audio- and video-recorded interviews exploring participants&#x2019; gameplay experience and attitudes toward AR.</p></sec><sec id="s2-5"><title>Physical Activity Assessments</title><p>To assess PA, an ActiGraph wGT3x-bt accelerometer (ActiGraph, Pensacola, FL) was attached to each participant&#x2019;s nondominant hip at a 60-Hz sampling rate, recording three-axis movement (anterior-posterior, vertical, and medial-lateral) [<xref ref-type="bibr" rid="ref60">60</xref>-<xref ref-type="bibr" rid="ref62">62</xref>]. The RAs documented the start and end times of each 10-minute gameplay period, using these timestamps to identify PA data for each game session. Data were downloaded via ActiLife software (version 6.13.2) and processed in 1-second epochs, a resolution appropriate for capturing short bursts of PA [<xref ref-type="bibr" rid="ref63">63</xref>]. Activity counts from all three axes and vector magnitude (VM) were extracted, and validated cut-point sets for older adults [<xref ref-type="bibr" rid="ref64">64</xref>] were applied to classify PA into light (&#x003C;2690 VM), moderate (&#x2265;2,690 to &#x003C;6,166 VM), and vigorous (&#x2265;6166 VM) (VPA) activity levels [<xref ref-type="bibr" rid="ref65">65</xref>].</p><p>A Polar HR monitor (Polar, Kempele, Finland) was used to continuously track PA intensity relative to each participant&#x2019;s age-predicted maximum HR [<xref ref-type="bibr" rid="ref66">66</xref>]. PA intensity was calculated using the HR reserve (HRR) formula [HRR=maximum HR (220-age)&#x2013;resting HR]. Intensity thresholds were defined as light (&#x003C;40% HRR), moderate (40%&#x2010;59% HRR), and vigorous PA (60%&#x2010;89% HRR) based on the American College of Sports Medicine guidelines [<xref ref-type="bibr" rid="ref67">67</xref>]. Individualized cutoff points were applied to determine time spent at each intensity level, with MVPA estimated calculated as the sum of moderate and vigorous PA durations. HR monitors provide a relative estimate of PA intensity while accelerometers will offer an absolute estimation, which is crucial for designing group-based intervention studies due to ease of use in free-living environments [<xref ref-type="bibr" rid="ref68">68</xref>-<xref ref-type="bibr" rid="ref71">71</xref>].</p></sec><sec id="s2-6"><title>Cognitive Assessments</title><p>Cognitive function was assessed using two NIH Toolbox (version 3) [<xref ref-type="bibr" rid="ref72">72</xref>] tests: the visual reasoning test and the Flanker inhibitory control and attention test. The visual reasoning test is an executive function assessment that evaluates nonverbal and visual reasoning, requiring participants to select the response option that is most like or missing from the target images displayed at the top of the screen. The Flanker inhibitory control and attention test measures inhibitory control and attention, where participants must focus on a particular stimulus while ignoring distracting flanking stimuli. See <xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref> for screenshots of both tests.</p><p>These assessments were administered twice&#x2014;before and after the gameplay&#x2014;to evaluate cognitive changes. For post-gameplay assessments, RAs ensured that each participant&#x2019;s HR returned to within waited for each participant&#x2019;s HR to drop to within 10 beats per minute (BPM) of their resting HR before initiating the cognitive tests, minimizing potential influences of elevated HR on cognitive performance.</p></sec><sec id="s2-7"><title>Questionnaires</title><p>Three surveys were used to assess participants&#x2019; PA intentions, motivations, and gaming experience: (1) The AAR/PA Intention Scale [<xref ref-type="bibr" rid="ref73">73</xref>] evaluates attitudes toward PA, perceived behavioral control, and intention to engage in PA. (2) The AAR/PA Motivation is measured by the PA Enjoyment Scale [<xref ref-type="bibr" rid="ref74">74</xref>]. (3) The Game Experience Questionnaire (GEQ) [<xref ref-type="bibr" rid="ref75">75</xref>] is a 33-item scale that evaluates gaming experience across multiple dimensions, including competence, immersion, and emotional responses. These validated instruments provide a comprehensive assessment of participants&#x2019; engagement with the AAR-based PA and the factors influencing their motivation and experience.</p></sec><sec id="s2-8"><title>Interviews</title><p>Before leaving the experimental session, participants took part in interviews to share their experiences with AAR games, including their overall impressions and interest in continued gameplay. RAs conducted the interviews using standardized questions that had been previously used in similar studies to ensure consistency and comparability across participants [<xref ref-type="bibr" rid="ref76">76</xref>,<xref ref-type="bibr" rid="ref77">77</xref>].</p></sec><sec id="s2-9"><title>Data Analyses&#x2003;</title><p>Quantitative data were analyzed using SPSS V.29 (IBM, SPSS Inc., Chicago, IL), with paired-sample <italic>t</italic> tests conducted to assess changes in PA levels and cognitive function. Data are presented as means and standard deviations. All survey questionnaires were scored and analyzed according to their original instructions. The AAR/PA Intention Scale (Cronbach <italic>&#x03B1;</italic>=0.96) [<xref ref-type="bibr" rid="ref73">73</xref>] and the PA Enjoyment Scale (Cronbach <italic>&#x03B1;</italic>=0.86) [<xref ref-type="bibr" rid="ref74">74</xref>] were calculated by averaging their respective items. All GEQ-derived variables were scored and analyzed per the developer&#x2019;s recommendation [<xref ref-type="bibr" rid="ref75">75</xref>], with subscales excluded from averaging if a Cronbach &#x03B1; was below 0.6 [<xref ref-type="bibr" rid="ref78">78</xref>]. Qualitative interview data were examined through thematic analysis to identify central themes and patterns in participants&#x2019; experiences.</p></sec></sec><sec id="s3" sec-type="results"><title>Results</title><sec id="s3-1"><title>Demographics</title><p>The average (SD) age of participants was 74.6 (3.73) years. The majority of participants were right-handed (15/16). Racial distribution was equal, with 8 participants identifying as White and 8 as Black; notably, the majority of White participants were male (5 of 8), whereas the majority of Black participants were female (6 of 8). Education levels varied, with the largest proportion holding a Bachelor&#x2019;s degree (31.25%; <xref ref-type="table" rid="table1">Table 1</xref>).</p><table-wrap id="t1" position="float"><label>Table 1.</label><caption><p>Demographics table, expressed as means and standard deviations.</p></caption><table id="table1" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Characteristic</td><td align="left" valign="bottom">Overall</td><td align="left" valign="bottom">Female</td><td align="left" valign="bottom">Male</td></tr></thead><tbody><tr><td align="left" valign="top">Number of participants, n (%)</td><td align="left" valign="top">16</td><td align="left" valign="top">9 (56.25)</td><td align="left" valign="top">7 (43.75)</td></tr><tr><td align="left" valign="top">Age (years), mean (SD)</td><td align="left" valign="top">74.6 (3.73)</td><td align="left" valign="top">74.22 (2.58)</td><td align="left" valign="top">75.14 (5.04)</td></tr><tr><td align="left" valign="top">Height (cm), mean (SD)</td><td align="left" valign="top">168.87 (10.12)</td><td align="left" valign="top">164 (6.5)</td><td align="left" valign="top">175.14 (10.88)</td></tr><tr><td align="left" valign="top">Weight (kg), mean (SD)</td><td align="left" valign="top">84.72 (13.14)</td><td align="left" valign="top">81.40 (12.18)</td><td align="left" valign="top">88.98 (14.02)</td></tr><tr><td align="left" valign="top">Dominant hand, n</td><td align="left" valign="top">Right = 15; Left = 1</td><td align="left" valign="top">Right = 9; Left = 0</td><td align="left" valign="top">Right = 6; Left = 1</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Right</td><td align="left" valign="top">15</td><td align="left" valign="top">9</td><td align="left" valign="top">6</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Left</td><td align="left" valign="top">1</td><td align="left" valign="top">0</td><td align="left" valign="top">1</td></tr><tr><td align="left" valign="top">Race, n</td><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;White</td><td align="left" valign="top">8</td><td align="left" valign="top">3</td><td align="left" valign="top">5</td></tr><tr><td align="left" valign="top">&#x2003;Black</td><td align="left" valign="top">8</td><td align="left" valign="top">6</td><td align="left" valign="top">2</td></tr><tr><td align="left" valign="top">Education level, n (%)</td><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/></tr><tr><td align="left" valign="top">&#x2003;High school graduate</td><td align="left" valign="top">3 (18.75)</td><td align="left" valign="top">2</td><td align="left" valign="top">1</td></tr><tr><td align="left" valign="top">&#x2003;Professional degree</td><td align="left" valign="top">3 (18.75)</td><td align="left" valign="top">3</td><td align="left" valign="top">0</td></tr><tr><td align="left" valign="top">&#x2003;Bachelor&#x2019;s</td><td align="left" valign="top">5 (31.25)</td><td align="left" valign="top">2</td><td align="left" valign="top">3</td></tr><tr><td align="left" valign="top">&#x2003;Master&#x2019;s</td><td align="left" valign="top">2 (12.5)</td><td align="left" valign="top">2</td><td align="left" valign="top">0</td></tr><tr><td align="left" valign="top">&#x2003;Doctorate</td><td align="left" valign="top">3 (18.75)</td><td align="left" valign="top">0</td><td align="left" valign="top">3</td></tr></tbody></table></table-wrap><p>The most prevalent health conditions among participants included high blood pressure and hypertension, with commonly prescribed medications such as amlodipine, losartan, and lisinopril. Statin therapy, including atorvastatin and rosuvastatin, was widely used for cholesterol management. Several participants have histories of significant cardiovascular events, including heart attacks, arrhythmias, and coronary artery stent placements. For instance, one participant experienced a heart attack 6 years ago, while another had stents inserted into the right coronary artery. Other common conditions include osteoarthritis, osteoporosis, and hypothyroidism, along with reports of past cancer diagnoses and respiratory issues. Notably, seven of the 16 participants reported taking beta-blockers, which could lead to underestimation of HR-based PA measurements [<xref ref-type="bibr" rid="ref79">79</xref>].</p></sec><sec id="s3-2"><title>Physical Activities and Zone of Exercise</title><p><xref ref-type="table" rid="table2">Table 2</xref> presents the time spent in various PA intensities&#x2014;light, moderate, and vigorous&#x2014;as recorded by the ActiGraph and Polar devices across four different games [<italic>Reaction Flow</italic>, <italic>Whack A Mole</italic>, <italic>Super Hits</italic> (<italic>Catch</italic>), and <italic>Super Hits</italic> (<italic>Slash</italic>)]. Although, as expected, vigorous PA levels were relatively low across both devices and all games, each game successfully induced, on average, 20%&#x2010;30% MVPA among participants.</p><table-wrap id="t2" position="float"><label>Table 2.</label><caption><p>Time spent in minutes in various PA levels using accelerometer and HR monitors, expressed as means and standard deviations.</p></caption><table id="table2" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom"/><td align="left" valign="bottom">Light</td><td align="left" valign="bottom">Moderate</td><td align="left" valign="bottom">Vigorous</td><td align="left" valign="bottom">MVPA<sup><xref ref-type="table-fn" rid="table2fn1">a</xref></sup></td></tr></thead><tbody><tr><td align="left" valign="top"><italic>Reaction Flow</italic></td><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>ActiGraph</td><td align="left" valign="top">3.57 (1.32)</td><td align="left" valign="top">2.73 (1.59)</td><td align="left" valign="top">0.73 (0.88)</td><td align="left" valign="top">3.46 (2.25)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Polar</td><td align="left" valign="top">2.39 (2.11)</td><td align="left" valign="top">2.20 (2.59)</td><td align="left" valign="top">0.62 (1.42)</td><td align="left" valign="top">2.81 (3.45)</td></tr><tr><td align="left" valign="top"><italic>Whack A Mole</italic></td><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>ActiGraph</td><td align="left" valign="top">3.76<sup><xref ref-type="table-fn" rid="table2fn2">b</xref></sup> (1.40)</td><td align="left" valign="top">2.21 (1.64)</td><td align="left" valign="top">0.55 (0.87)</td><td align="left" valign="top">2.77 (2.31)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Polar</td><td align="left" valign="top">1.81<sup><xref ref-type="table-fn" rid="table2fn2">b</xref></sup> (1.76)</td><td align="left" valign="top">3.66 (3.49)</td><td align="left" valign="top">0.48 (1.18)</td><td align="left" valign="top">4.14 (3.96)</td></tr><tr><td align="left" valign="top"><italic>Super Hits (Catch</italic>)</td><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>ActiGraph</td><td align="left" valign="top">3.61 (1.68)</td><td align="left" valign="top">1.42 (1.57)</td><td align="left" valign="top">0.12 (0.17)</td><td align="left" valign="top">1.53 (1.71)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Polar</td><td align="left" valign="top">2.37 (2.00)</td><td align="left" valign="top">1.70 (2.29)</td><td align="left" valign="top">0.73 (1.83)</td><td align="left" valign="top">2.43 (3.41)</td></tr><tr><td align="left" valign="top"><italic>Super Hits (Slash</italic>)</td><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>ActiGraph</td><td align="left" valign="top">4.03 (1.53)</td><td align="left" valign="top">1.15 (1.57)</td><td align="left" valign="top">0.08 (0.11)</td><td align="left" valign="top">1.23<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup> (1.65)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Polar</td><td align="left" valign="top">3.08 (1.84)</td><td align="left" valign="top">2.34 (2.33)</td><td align="left" valign="top">0.75 (1.97)</td><td align="left" valign="top">3.09<sup><xref ref-type="table-fn" rid="table2fn3">c</xref></sup> (3.28)</td></tr><tr><td align="left" valign="top">Overall average</td><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>ActiGraph</td><td align="left" valign="top">3.74<sup><xref ref-type="table-fn" rid="table2fn4">d</xref></sup> (0.21)</td><td align="left" valign="top">1.88 (0.73)</td><td align="left" valign="top">0.37 (0.32)</td><td align="left" valign="top">2.25 (1.05)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Polar</td><td align="left" valign="top">2.41<sup><xref ref-type="table-fn" rid="table2fn4">d</xref></sup> (0.52)</td><td align="left" valign="top">2.47 (0.84)</td><td align="left" valign="top">0.65 (0.12)</td><td align="left" valign="top">3.12 (0.73)</td></tr></tbody></table><table-wrap-foot><fn id="table2fn1"><p><sup>a</sup>MVPA: moderate-to-vigorous physical activity</p></fn><fn id="table2fn2"><p><sup>b</sup><italic>P</italic>=.005</p></fn><fn id="table2fn3"><p><sup>c</sup><italic>P</italic>=.02</p></fn><fn id="table2fn4"><p><sup>d</sup><italic>P</italic>=.003</p></fn></table-wrap-foot></table-wrap><p>Notably, Polar recorded higher MVPA times for most games compared to ActiGraph, except for <italic>Reaction Flow</italic>. ActiGraph consistently recorded higher light PA levels, particularly for <italic>Whack A Mole</italic> (Light<sub>ActiGraph</sub>=3.76 [SD 1.40] versus Light<sub>Polar</sub>=1.81 [SD 1.76]; <italic>P</italic>=.005) and for the overall average (Light<sub>ActiGraph</sub>= 3.74 [SD 0.21] versus Light<sub>Polar</sub>=2.41 [SD 0.52]; <italic>P</italic>=.003). <italic>Whack A Mole</italic> had the highest MVPA per Polar, 4.14 (SD 3.96) minutes, while <italic>Reaction Flow</italic> had the highest MVPA per ActiGraph, 3.46 (SD 2.25) minutes. The difference between the two PA measurement devices was statistically significant only for <italic>Super Hits</italic> (<italic>Slash</italic>) (MVPA<sub>ActiGraph</sub>=1.23 [SD 1.65] versus MVPA<sub>Polar</sub>=3.09 [SD 3.28]; <italic>P</italic>=.02).</p><p><xref ref-type="table" rid="table3">Table 3</xref> presents the average time participants spent in different zones within the 8&#x00D7;8 ft space. The majority of gameplay time occurred in Zone 1 (4&#x00D7;4 ft), where participants spent an average of 30.01 (SD 2.14) minutes, accounting for 75% of total gameplay. Zone 2 (6&#x00D7;6 ft) was used moderately, with participants spending 9.15 (SD 1.80) minutes (23% of total gameplay), while Zone 3 (8&#x00D7;8 ft) was rarely used, with only 0.93 (SD 0.35) minutes (2%). This distribution suggests a strong tendency for participants to remain within the smallest zone, highlighting the feasibility of playing these AAR games in constrained spaces, making them particularly suitable for home environments. Additionally, the limited movement across zones suggests that balance, rather than extensive mobility, can be more critical to gameplay, thereby lowering spatial barriers to engaging in PA.</p><table-wrap id="t3" position="float"><label>Table 3.</label><caption><p>Duration spent in different zones in minutes, expressed as means and standard deviations.</p></caption><table id="table3" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom"/><td align="left" valign="bottom">Reaction Flow</td><td align="left" valign="bottom">Whack a Mole</td><td align="left" valign="bottom">Super Hits (Catch)</td><td align="left" valign="bottom">Super Hits (Slash)</td><td align="left" valign="bottom">Total duration</td><td align="left" valign="bottom">% of time spent</td></tr></thead><tbody><tr><td align="left" valign="top">Zone 1: 4&#x00D7;4 ft</td><td align="left" valign="top">4.30 (4.14)</td><td align="left" valign="top">8.68 (2.73)</td><td align="left" valign="top">8.39 (3.33)</td><td align="left" valign="top">8.63 (3.15)</td><td align="left" valign="top">30.00 (2.14)</td><td align="left" valign="top">75</td></tr><tr><td align="left" valign="top">Zone 2: 6&#x00D7;6 ft</td><td align="left" valign="top">4.97 (3.66)</td><td align="left" valign="top">1.16 (2.18)</td><td align="left" valign="top">1.64 (3.34)</td><td align="left" valign="top">1.39 (3.15)</td><td align="left" valign="top">9.15 (1.80)</td><td align="left" valign="top">23</td></tr><tr><td align="left" valign="top">Zone 3: 8&#x00D7;8 ft</td><td align="left" valign="top">0.75 (1.63)</td><td align="left" valign="top">0.18 (0.67)</td><td align="left" valign="top">0.00 (0.00)</td><td align="left" valign="top">0.00 (0.00)</td><td align="left" valign="top">0.93 (0.35)</td><td align="left" valign="top">2</td></tr><tr><td align="left" valign="top">Total</td><td align="left" valign="top">10.02 (2.27)</td><td align="left" valign="top">10.02 (4.65)</td><td align="left" valign="top">10.03 (4.45)</td><td align="left" valign="top">10.02 (4.64)</td><td align="left" valign="top">40.00 (0.10)</td><td align="left" valign="top">100</td></tr></tbody></table></table-wrap></sec><sec id="s3-3"><title>Heart Rate and Rate of Perceived Exertion</title><p>All HR values collected during the protocol (in both BPM and %HRmax) reflect averages calculated from second-by-second readings. Before cognitive testing, participants&#x2019; HR averaged 75.75 (SD 12.85) BPM, with minimal exertion (RPE=0.12, SD 0.5). After the initial test, HR decreased to 72.25 (SD 12.32) BPM when RPE rose modestly to 0.43 (SD 0.72). Prior to gameplay, HR remained stable at 72.31 (SD 12.89) BPM, with a slight RPE increase to 0.62 (SD 0.71).</p><p>During gameplay, HR rose significantly to an average of 100 (SD 14.11) BPM, with post-gameplay RPE immediately increasing to 3.25 (SD 1.73), indicating moderate-to-high physical exertion. This converts to an average of 64.1% HR<sub>Max</sub> during the gameplay, indicating that the gameplay on average elicited moderate PA [<xref ref-type="bibr" rid="ref67">67</xref>]. The gameplay phase lasted approximately 40 minutes. In addition, participants rested for an average of 8.73 minutes (SD 3.70, range 2&#x2010;25) between each game to allow for HR recovery.</p><p>Before the post-cognitive test, HR remained somewhat elevated at 80.31 (SD 14.75) BPM with an RPE of 1.62 (SD 1.74), indicating lingering physical exertion effects. The RAs ensured that participants&#x2019; HR dropped within 10 BPM of resting HR before initiating the cognitive test. After the test, HR returned closer to baseline at 76 (SD 13.24) BPM and RPE decreased to 1.42 (SD 1.96). See <xref ref-type="table" rid="table4">Table 4</xref> for details.</p><table-wrap id="t4" position="float"><label>Table 4.</label><caption><p>Heart rate and rate of perceived exertion, expressed as means and standard deviations.</p></caption><table id="table4" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Sequence and variables</td><td align="left" valign="bottom">Value</td></tr></thead><tbody><tr><td align="left" valign="top">Pre-cog tests</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Age-predicted maximum HR<sup><xref ref-type="table-fn" rid="table4fn1">a</xref></sup> (HR<sub>Max)</sub></td><td align="left" valign="top">156.01 (2.63)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Before pre-cog HR (BPM<sup><xref ref-type="table-fn" rid="table4fn2">b</xref></sup>)</td><td align="left" valign="top">75.75 (12.85)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Before pre-cog %HR<sub>Max</sub></td><td align="left" valign="top">48.55</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Before pre-cog RPE<sup><xref ref-type="table-fn" rid="table4fn3">c</xref></sup> (scale)</td><td align="left" valign="top">0.12 (0.5)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>After pre-cog HR (BPM)</td><td align="left" valign="top">72.25 (12.32)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>After pre-cog %HR<sub>Max</sub></td><td align="left" valign="top">46.31</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>After pre-cog RPE (scale)</td><td align="left" valign="top">0.43 (0.72)</td></tr><tr><td align="left" valign="top">Before gameplay</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>HR (BPM)</td><td align="left" valign="top">72.31 (12.89)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Before gameplay %HR<sub>Max</sub></td><td align="left" valign="top">46.34</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>RPE (scale)</td><td align="left" valign="top">0.62 (0.71)</td></tr><tr><td align="left" valign="top">During gameplay</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Duration (mins)</td><td align="left" valign="top">40.00 (0.10)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>HR during Game 1 (BPM)</td><td align="left" valign="top">100.00 (14.76)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>%HR<sub>Max</sub> during Game 1 (%)</td><td align="left" valign="top">64.10</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>HR during Game 2 (BPM)</td><td align="left" valign="top">100.01 (14.96)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>%HR<sub>Max</sub> during Game 2 (%)</td><td align="left" valign="top">64.10</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>HR during Game 3 (BPM)</td><td align="left" valign="top">100.25 (14.35)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>%HR<sub>Max</sub> during Game 3 (%)</td><td align="left" valign="top">64.26</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>HR during Game 4 (BPM)</td><td align="left" valign="top">98.69 (14.71)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>%HR<sub>Max</sub> during Game 4 (%)</td><td align="left" valign="top">63.26</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>HR per game (BPM)</td><td align="left" valign="top">100.00 (14.11)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>%HR<sub>Max</sub> during all gameplay (%)</td><td align="left" valign="top">64.10</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Resting time for HR recovery (min)</td><td align="left" valign="top">8.73 (3.70)</td></tr><tr><td align="left" valign="top">After gameplay</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>HR (BPM)</td><td align="left" valign="top">98.87 (16.82)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>After gameplay %HR<sub>Max</sub></td><td align="left" valign="top">63.37</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>RPE (scale)</td><td align="left" valign="top">3.25 (1.73)</td></tr><tr><td align="left" valign="top">Post-cog tests</td><td align="left" valign="top"/></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Resting time for HR recovery (min)</td><td align="left" valign="top">7.26 (3.77)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Before post-cog HR (BPM)</td><td align="left" valign="top">80.31 (14.75)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Before post-cog %HR<sub>Max</sub></td><td align="left" valign="top">51.48</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>Before post-cog RPE (scale)</td><td align="left" valign="top">1.62 (1.74)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>After post-cog HR (BPM)</td><td align="left" valign="top">76 (13.24)</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>After post-cog %HR<sub>Max</sub></td><td align="left" valign="top">48.71</td></tr><tr><td align="left" valign="top"><named-content content-type="indent">&#x00A0;&#x00A0;&#x00A0;&#x00A0;</named-content>After post-cog RPE (scale)</td><td align="left" valign="top">1.42 (1.96)</td></tr></tbody></table><table-wrap-foot><fn id="table4fn1"><p><sup>a</sup>HR: heart rate</p></fn><fn id="table4fn2"><p><sup>b</sup>BPM: beats per minute.</p></fn><fn id="table4fn3"><p><sup>c</sup>RPE: rate of perceived exertion.</p></fn></table-wrap-foot></table-wrap><p>Notably, the beta-blocker group consistently exhibited lower HR throughout the study&#x2014;approximately 8 BPM less on average&#x2014;compared to the non-taker group. Given that continuous RPE reporting during gameplay would have been disruptive, RPE was measured immediately after each game, following prior literature [<xref ref-type="bibr" rid="ref80">80</xref>-<xref ref-type="bibr" rid="ref82">82</xref>]. Additionally, they reported higher post-gameplay RPE than nontakers, though neither the HR nor RPE differences reached statistical significance due to the small sample sizes (7 takers vs 9 nontakers). Nevertheless, the mean values of average %HR<sub>Max</sub> suggest that those not on beta-blockers generally met the moderate-intensity threshold during games, whereas those on beta-blockers tended to fall slightly below the moderate intensity threshold. As such, the data were presented in aggregate below (see <xref ref-type="supplementary-material" rid="app3">Multimedia Appendix 3</xref> for a breakdown between the two groups).</p></sec><sec id="s3-4"><title>Cognitive Tests</title><p>&#x2003;The cognitive assessment, including the Flanker and visual reasoning tests, was conducted pre- and post-AAR gameplay to evaluate potential cognitive benefits. Visual reasoning scores improved significantly post-play (<italic>P</italic>=.04) in change-sensitive score (CSS), an item response theory&#x2013;based score metric designed for longitudinal change monitoring. Starting from NIH Toolbox V3, age- and education-adjusted <italic>T</italic> scores are also provided [<xref ref-type="bibr" rid="ref83">83</xref>]. The effect remained significant when adjusted by age alone and age and education combined (<italic>P</italic>&#x2019;s = .03). See <xref ref-type="table" rid="table5">Table 5</xref> for details. These results may suggest that visual reasoning abilities benefited from brief single-bout AAR gameplay, possibly due to the interactive, visually stimulating nature of the activities. However, an alternative explanation is that the improvement may be attributed to a practice effect on the task. To distinguish between these two possibilities, future studies should incorporate a control group to isolate the specific cognitive effects of AAR interventions.</p><table-wrap id="t5" position="float"><label>Table 5.</label><caption><p>Cognitive tests (Flanker and visual reasoning) before and after AAR<sup><xref ref-type="table-fn" rid="table5fn1">a</xref></sup> Play, expressed as means and standard deviations.</p></caption><table id="table5" frame="hsides" rules="groups"><thead><tr><td align="left" valign="top">Cognitive test</td><td align="left" valign="bottom">Before</td><td align="left" valign="bottom">After</td><td align="left" valign="bottom"><italic>T</italic></td><td align="left" valign="bottom"><italic>P</italic></td></tr></thead><tbody><tr><td align="left" valign="top">Flanker CSS<sup><xref ref-type="table-fn" rid="table5fn2">b</xref></sup></td><td align="left" valign="top">503.81 (19.17)</td><td align="left" valign="top">501.81 (15.39)</td><td align="left" valign="top">0.76</td><td align="left" valign="top">.23</td></tr><tr><td align="left" valign="top">Flanker age adjusted standard score</td><td align="left" valign="top">105.69 (21.98)</td><td align="left" valign="top">103.44 (17.60)</td><td align="left" valign="top">0.73</td><td align="left" valign="top">.24</td></tr><tr><td align="left" valign="top">Flanker age edu adjusted standard score</td><td align="left" valign="top">53.50 (14.89)</td><td align="left" valign="top">51.94 (11.81)</td><td align="left" valign="top">0.73</td><td align="left" valign="top">.24</td></tr><tr><td align="left" valign="top">Visual reasoning CSS<sup><xref ref-type="table-fn" rid="table5fn2">b</xref></sup></td><td align="left" valign="top">499.5 (8.52)</td><td align="left" valign="top">502.69 (10.66)</td><td align="left" valign="top">1.94<sup><xref ref-type="table-fn" rid="table5fn3">c</xref></sup></td><td align="left" valign="top">.04<sup><xref ref-type="table-fn" rid="table5fn3">c</xref></sup></td></tr><tr><td align="left" valign="top">Visual reasoning age adjusted standard score</td><td align="left" valign="top">102.88 (17.17)</td><td align="left" valign="top">109.31 (21.89)</td><td align="left" valign="top">1.98<sup><xref ref-type="table-fn" rid="table5fn3">c</xref></sup></td><td align="left" valign="top">.03<sup><xref ref-type="table-fn" rid="table5fn3">c</xref></sup></td></tr><tr><td align="left" valign="top">Visual reasoning age edu adjusted standard score</td><td align="left" valign="top">50.44 (10.01)</td><td align="left" valign="top">54.25 (12.08)</td><td align="left" valign="top">1.99<sup><xref ref-type="table-fn" rid="table5fn3">c</xref></sup></td><td align="left" valign="top">.03<sup><xref ref-type="table-fn" rid="table5fn3">c</xref></sup></td></tr></tbody></table><table-wrap-foot><fn id="table5fn1"><p><sup>a</sup>AAR: active augmented reality</p></fn><fn id="table5fn2"><p><sup>b</sup>CSS: change-sensitive score</p></fn><fn id="table5fn3"><p><sup>c</sup><italic>P</italic>&#x003C;.05</p></fn></table-wrap-foot></table-wrap></sec><sec id="s3-5"><title>Questionnaire Results</title><p><xref ref-type="table" rid="table6">Table 6</xref> summarizes participants&#x2019; responses across scales measuring AAR/PA motivation, intention, and game engagement. The AAR/PA intention score was 4.15 (SD 0.59) on a 5-point scale, reflecting a strong intention to continue engaging in AAR activities. Similarly, the AAR/PA motivation scale had a high mean score of 5.67 (SD 1.24) on a 7-point scale, suggesting participants were motivated to continue playing AAR games. In the GEQ subscales (5-point scale), all subscales except flow had an acceptable Cronbach &#x03B1; (&#x2265;0.6) and were averaged. Participants reported high positive affect, 4.35 (SD 0.80), and minimal negative affect, 1.30 (SD 0.46), with low tension, 1.25 (SD 0.67), suggesting that gameplay was generally enjoyable and nonstressful. They also reported relatively high competence 3.68 (SD 0.92) and sensory and imaginative immersion 3.64 (SD 0.88), showing that they felt capable and engaged during gameplay. The challenge level was moderate at 2.49 (SD 0.76), reflecting a manageable level of difficulty.</p><table-wrap id="t6" position="float"><label>Table 6.</label><caption><p>Survey results for the AAR<sup><xref ref-type="table-fn" rid="table6fn1">a</xref></sup>/PA<sup><xref ref-type="table-fn" rid="table6fn2">b</xref></sup> intention, motivation, and Game Experience Questionnaire (GEQ) measures, expressed as means and standard deviations<sup><xref ref-type="table-fn" rid="table6fn3">c</xref></sup>.</p></caption><table id="table6" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Survey result</td><td align="left" valign="bottom">Mean (SD)</td><td align="left" valign="bottom">Cronbach &#x03B1;</td></tr></thead><tbody><tr><td align="left" valign="top">AAR /PA intention</td><td align="left" valign="top">4.15 (0.59)</td><td align="left" valign="top">.86</td></tr><tr><td align="left" valign="top">AAR/PA motivation</td><td align="left" valign="top">5.67 (1.24)</td><td align="left" valign="top">.96</td></tr><tr><td align="left" valign="top">GEQ</td><td align="left" valign="top"/><td align="left" valign="top"/></tr><tr><td align="left" valign="top">Competence</td><td align="left" valign="top">3.68 (0.92)</td><td align="left" valign="top">.88</td></tr><tr><td align="left" valign="top">Sensory and imaginative immersion</td><td align="left" valign="top">3.64 (0.88)</td><td align="left" valign="top">.81</td></tr><tr><td align="left" valign="top">Flow</td><td align="left" valign="top">&#x2014;</td><td align="left" valign="top">.43</td></tr><tr><td align="left" valign="top">Tension</td><td align="left" valign="top">1.25 (0.67)</td><td align="left" valign="top">.86</td></tr><tr><td align="left" valign="top">Challenge</td><td align="left" valign="top">2.49 (0.76)</td><td align="left" valign="top">.67</td></tr><tr><td align="left" valign="top">Negative affect</td><td align="left" valign="top">1.30 (0.46)</td><td align="left" valign="top">.83</td></tr><tr><td align="left" valign="top">Positive affect</td><td align="left" valign="top">4.35 (0.80)</td><td align="left" valign="top">.82</td></tr></tbody></table><table-wrap-foot><fn id="table6fn1"><p><sup>a</sup>AAR: active augmented reality</p></fn><fn id="table6fn2"><p><sup>b</sup>PA: physical activity</p></fn><fn id="table6fn3"><p><sup>c</sup>All scales are 5-point scales except for AAR/PA motivation, which is a 7-point scale.</p></fn></table-wrap-foot></table-wrap></sec><sec id="s3-6"><title>Interview Analysis</title><p>&#x2003;We used a thematic analysis approach to examine the qualitative interview data. Two team members independently reviewed the transcripts and conducted open coding to identify initial patterns. Codes were refined through discussion, and themes were inductively developed to reflect key participant perceptions of AAR gameplay, such as enjoyment, accessibility, physical challenge, and suggestions for improvement.</p><p>The thematic analysis revealed that older adult participants generally responded positively to the AR games, viewing them as both enjoyable and beneficial for combining physical exercise with mental engagement. Many appreciated the opportunity to play at home, describing it as an accessible and refreshing alternative to traditional exercise settings. While some initially had reservations about the novelty of AR or the perceived cost of setup, these concerns diminished with familiarity. Additionally, participants expressed a desire for more physically exerting games than those provided. Among the games played, <italic>Whack a Mole</italic> emerged as a favorite, with participants appreciating its simplicity and engaging nature. The interactive experience, particularly the combination of music and movement, was highlighted as a factor that fostered focus and enjoyment.</p><p>Looking ahead to future game design, participants expressed interest in customizable games that start at an easier level and progressively increase in difficulty, accommodating a range of physical abilities. Many suggested incorporating full-body movements and immersive environments, such as outdoor simulations, to further enhance engagement. Music integration, particularly with familiar tunes, was another highly requested feature. Beyond individual play, participants saw great potential for these games in supporting physical and mental health, particularly for older adults or individuals with limited mobility, ensuring a user-friendly interface for those less familiar with technology and incorporating community or group-based settings to foster social engagement and support.</p></sec></sec><sec id="s4" sec-type="discussion"><title>Discussion</title><sec id="s4-1"><title>Principal Findings</title><p>This feasibility study highlights the potential of AAR games to increase PA and enhance cognitive function among older adults in a user-friendly and safe environment. Participants engaged in MVPA during gameplay, as measured by accelerometers and HR monitors, aligning with the recommended PA levels for older adults. Cognitive assessments revealed significant improvements in visual reasoning, indicating potential cognitive benefits from a single bout of AAR gameplay. Surveys indicated high levels of motivation, enjoyment, and positive emotions associated with AAR gameplay, with participants appreciating its accessibility and suitability for free-living environments. Interview feedback emphasized the need for adaptable game designs to cater to diverse physical abilities and individual preferences. Importantly, despite their various health conditions, all participants successfully completed the study protocol, underscoring the feasibility and acceptability of AAR for the older adult population.</p></sec><sec id="s4-2"><title>Comparison to Prior Research</title><p>Our findings revealed differences in PA measurement between devices, with the HR monitor, Polar, recording slightly higher MVPA levels compared to the accelerometer, ActiGraph. Since HR-based measurements offer a more individualized measurement of PA intensity, MVPA estimates from Polar may provide a more appropriate reflection of exertion levels, whereas ActiGraph measures may be more appropriate on a group but not individual level [<xref ref-type="bibr" rid="ref84">84</xref>,<xref ref-type="bibr" rid="ref85">85</xref>]. However, given that 7 out of 16 participants were taking beta-blockers, their actual MVPA level may have been higher than what the Polar has recorded, as beta-blockers can suppress HR responses to physical exertion [<xref ref-type="bibr" rid="ref79">79</xref>]. These variations in PA measurement emphasize the need for careful selection of appropriate tracking methods in future AAR studies among older adults, particularly when accounting for medication effects on HR-based PA assessments.</p><p>Beyond the benefits afforded by the PA engagement, AAR gameplay also improved cognitive function, with significant gains in visual reasoning. This suggests that the AAR games may enhance cognitive processes related to problem-solving and cognitive flexibility. These results align with prior research linking PA to enhanced executive function, indicating that AAR games could stimulate brain regions associated with higher-order cognition and promote neural engagement [<xref ref-type="bibr" rid="ref59">59</xref>,<xref ref-type="bibr" rid="ref86">86</xref>,<xref ref-type="bibr" rid="ref87">87</xref>]. While these effects may be attributed to AAR gameplay, the possibility of a practice effect on cognitive testing cannot be ruled out. Future studies should incorporate control groups to better isolate the specific cognitive effects of AAR interventions.</p><p>One of the most notable advantages of AAR gameplay is its accessibility and practicality for home-based exercise. Participants remained engaged and motivated, as reflected by their high AAR/PA intention and motivation scores, along with strong positive affect and immersion ratings. With initial training and a play environment designed to simulate the home environment, participants were able to engage in PA with minimal equipment and space requirements. Notably, the majority of the gameplay occurred within a 4&#x00D7;4 area (Zone 1), highlighting AAR&#x2019;s feasibility in confined spaces and its potential to reduce barriers to PA among those with limited access to outdoor exercise spaces. Additionally, since AAR gameplay relies more on balance than extensive mobility, it offers a viable exercise option for individuals with physical limitations [<xref ref-type="bibr" rid="ref28">28</xref>].</p><p>The qualitative findings further support these conclusions, with participants expressing enthusiasm for AAR games as a viable alternative to traditional exercise. Many appreciated the interactive nature of the games, particularly the integration of music and movement, and welcomed the flexibility of playing in a home-like environment. While some initially faced challenges with gameplay mechanics, their confidence improved over time, and they expressed interest in continued gameplay. Participants also suggested various customization options, such as adjustable difficulty levels, which could enhance long-term engagement and accommodate physical abilities.</p></sec><sec id="s4-3"><title>Limitations</title><p>&#x2003;This study has several limitations. First, the small sample size (n=16), along with the relatively short duration, reduces statistical power and limits the generalizability of the findings, warranting larger-scale studies conducted over a longer period. Future research should aim to recruit a more representative sample. Second, 7 out of 16 participants were taking beta blockers, which may have influenced HR-based PA assessments and potentially led to underestimation of MVPA levels, as reflected in the lower %HR<sub>max</sub> observed among takers compared to nontakers. Future research should explore alternative PA measurement methods or incorporate personalized adjustments for HR thresholds in individuals taking beta blockers. Although alternative PA measurement strategies or individualized adjustments to HR thresholds should be explored, to date, no widely accepted method exists for adjusting HR-based PA estimates among beta-blocker users. A larger sample and auxiliary measures such as RPE with a larger sample in both groups might help shed light on the PA intensity levels. Third, the lack of a control group prevents us from drawing causal conclusions regarding cognitive improvements from AAR gameplay. Future studies should include appropriate comparison conditions, such as passive and active control groups, to better isolate the cognitive effects of AAR interventions and strengthen causal inferences.</p></sec><sec id="s4-4"><title>Future Directions</title><p>Given the feasibility-focused nature of the study, we intentionally selected games with more moderate than vigorous PA intensities to prioritize safety. Despite this, several participants expressed a desire for more intense PA options, indicating that older adults may benefit from progressively vigorous AAR gameplay as they grow more comfortable with technology and gradually increase their PA levels. Although appropriate for a feasibility trial, this constrained intensity range may have limited the extent of cognitive changes observed, particularly if higher-intensity PA is a necessary condition for eliciting measurable cognitive benefit, though careful precautions are needed to ensure that high-intensity exercise is not potentially dangerous for older adults who are not regular exercisers. Future research should explore adaptive difficulty settings to allow for gradual progression in PA intensity, accommodating users at different fitness levels. In addition, future studies should examine a wider variety of AAR game types, longer intervention periods, and group-based gameplay to explore potential social and motivational benefits.</p></sec><sec id="s4-5"><title>Conclusions</title><p>Using a mixed-methods one-group pretest-posttest experimental design, the study demonstrated that older adults could engage in MVPA during AAR gameplay and showed significant improvements in visual reasoning. Participants reported high levels of motivation, enjoyment, and positive affect, and qualitative feedback further supported the acceptability and potential benefits of AAR interventions. These findings underscore the need for further exploration of long-term AAR interventions with larger, controlled trials to evaluate the sustained effects and optimize design features. With continued development and refinement, AAR games may serve as a viable and acceptable intervention tool for promoting PA and cognitive engagement among older adults.</p></sec></sec></body><back><ack><p>This study was supported in part by a grant from the National Institute of Diabetes and Digestive and Kidney Diseases (R01DK109316, PI: ASL) and by the College of Arts, Media, and Design and Bouv&#x00E9; College of Health Sciences at Northeastern University, Boston, MA.</p></ack><notes><sec><title>Data Availability</title><p>The datasets used or analyzed during the current study are available from the corresponding author on reasonable request.</p></sec></notes><fn-group><fn fn-type="con"><p>ASL has contributed to Funding acquisition, Conceptualization, Methodology, Resources, Supervision, Project administration, Formal analysis, Writing&#x2013;original draft, and Writing&#x2013;review &#x0026; editing. BP and SG contributed in Investigation, Data curation, and Writing&#x2013;original draft. SH has contributed to Investigation and Writing&#x2013;original draft. DP was responsible for Methodology. AFK was responsible for Methodology, Resources, and Writing&#x2013;review &#x0026; editing. All authors have read and approved the final version of the manuscript and agree with the order of presentation of the authors.</p></fn><fn fn-type="conflict"><p>None declared.</p></fn></fn-group><glossary><title>Abbreviations</title><def-list><def-item><term id="abb1">AAR</term><def><p>active augmented reality</p></def></def-item><def-item><term id="abb2">AR</term><def><p>augmented reality</p></def></def-item><def-item><term id="abb3">AVG</term><def><p>active video game</p></def></def-item><def-item><term id="abb4">BPM</term><def><p>beats per minute</p></def></def-item><def-item><term id="abb5">GEQ</term><def><p>Gaming Experience Questionnaire</p></def></def-item><def-item><term id="abb6">HR</term><def><p>heart rate</p></def></def-item><def-item><term id="abb7">HRR</term><def><p>heart rate reserve</p></def></def-item><def-item><term id="abb8">IGNITE</term><def><p>Investigating Gains in Neurocognition in an Intervention Trial of Exercise</p></def></def-item><def-item><term id="abb9">MVPA</term><def><p>moderate-to-vigorous physical activity</p></def></def-item><def-item><term id="abb10">PA</term><def><p>physical activity</p></def></def-item><def-item><term id="abb11">RA</term><def><p>research assistants</p></def></def-item><def-item><term id="abb12">RPE</term><def><p>rate of perceived exertion</p></def></def-item><def-item><term id="abb13">RQ</term><def><p>research question</p></def></def-item><def-item><term id="abb14">VM</term><def><p>vector magnitude</p></def></def-item><def-item><term id="abb15">VR</term><def><p>virtual reality</p></def></def-item></def-list></glossary><ref-list><title>References</title><ref id="ref1"><label>1</label><nlm-citation citation-type="report"><person-group person-group-type="author"><name name-style="western"><surname>Vincent</surname><given-names>GK</given-names> </name><name name-style="western"><surname>Velkoff</surname><given-names>VA</given-names> </name></person-group><article-title>The next four decades: the older 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id="app1"><label>Multimedia Appendix 1</label><p>Online questionnaire.</p><media xlink:href="games_v13i1e73221_app1.docx" xlink:title="DOCX File, 20 KB"/></supplementary-material><supplementary-material id="app2"><label>Multimedia Appendix 2</label><p>Screenshots of the visual reasoning (Up) and the Flanker inhibitory control and attention tests (Down).</p><media xlink:href="games_v13i1e73221_app2.docx" xlink:title="DOCX File, 75 KB"/></supplementary-material><supplementary-material id="app3"><label>Multimedia Appendix 3</label><p>Heart rate and rate of perceived exertion between beta-blocker nonusers and users, expressed as means and standard deviations.</p><media xlink:href="games_v13i1e73221_app3.docx" xlink:title="DOCX File, 19 KB"/></supplementary-material></app-group></back></article>