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Home-Based Nonimmersive Virtual Reality Training After Discharge From Inpatient or Outpatient Stroke Rehabilitation: Parallel  Feasibility Randomized Controlled Trial

Home-Based Nonimmersive Virtual Reality Training After Discharge From Inpatient or Outpatient Stroke Rehabilitation: Parallel Feasibility Randomized Controlled Trial

Patients were eligible if they were approaching discharge from either inpatient or outpatient stroke rehabilitation, with the intent that they would participate post discharge. While there was no eligibility criterion regarding the chronicity of stroke, inpatient and outpatient stroke rehabilitation at this facility was generally reserved for patients in the subacute phase after stroke.

Lisa Sheehy, Anne Taillon-Hobson, Heidi Sveistrup, Martin Bilodeau, Christine Yang, Vivian Welch, Hillel Finestone

JMIR Rehabil Assist Technol 2025;12:e64729

Toward Unsupervised Capacity Assessments for Gait in Neurorehabilitation: Validation Study

Toward Unsupervised Capacity Assessments for Gait in Neurorehabilitation: Validation Study

More than 80% of stroke survivors experience gait impairments, and between 55% and 75% continue to experience functional problems 3 to 6 months after their stroke [1,2]. These impairments frequently lead to reduced activity levels and diminished community participation [3-5]. Due to this, one of the most common goals in gait rehabilitation is to enhance functional independence and quality of life [3,6-8].

Aileen C Naef, Guichande Duarte, Saskia Neumann, Migjen Shala, Meret Branscheidt, Chris Easthope Awai

J Med Internet Res 2025;27:e66123

Examining the Efficacy of the Telehealth Assessment and Skill-Building Kit (TASK III) Intervention for Stroke Caregivers: Protocol for a Randomized Controlled Clinical Trial

Examining the Efficacy of the Telehealth Assessment and Skill-Building Kit (TASK III) Intervention for Stroke Caregivers: Protocol for a Randomized Controlled Clinical Trial

Each year, approximately 795,000 Americans experience a stroke, which is a leading cause of serious, long-term disability [1]. Because of disability, approximately 68% to 74% of stroke survivors require the care of family members [2,3], who are suddenly thrust into providing care without receiving proper training from health care providers [4-6].

Tamilyn Bakas, Elaine Miller, Heidi Sucharew, Natalie Kreitzer, Jahmeel Israel, Matthew Rota, Brett Harnett, Kari Dunning, Holly Jones, Michael McCarthy, Bonnie Brehm, Joan K Austin, Pamela H Mitchell

JMIR Res Protoc 2025;14:e67219

The Lived Experience of Participating in Online Peer-To-Peer Groups After Acquired Brain Injury: Phenomenological Study

The Lived Experience of Participating in Online Peer-To-Peer Groups After Acquired Brain Injury: Phenomenological Study

Stroke is a leading cause of disability, and the disability-adjusted life-years for stroke indicate that it increases both mortality and the risk of living with lifelong disabilities [3]. Life after a stroke can entail challenging experiences for the stroke survivor, both in the recovery of functions as well as in learning to live with visible or invisible disabilities, which may persist and impact their own lives [4-6] as well as those of their loved ones [7].

Malin Tistad, Lill Hultman, Annica Wohlin Wottrich, Lena von Koch

J Med Internet Res 2025;27:e67658

A Game-Based Mechatronic Device for Digital Rehabilitation of Hand Function After a Stroke: Design, Prototyping, and Feasibility Study

A Game-Based Mechatronic Device for Digital Rehabilitation of Hand Function After a Stroke: Design, Prototyping, and Feasibility Study

In this paper, we first describe the RMD hardware and gaming software, its functionality, and related applications to provide both treatment and assessment of recovery programs targeting the manual dexterity of people after a stroke. The objective of this study is to present the results of a proof-of-principle pilot study conducted on 5 patients with stroke to examine the feasibility and benefits of a 6-week game-based exercise program using the RMD.

Anuprita Kanitkar, Nariman Sepehri, Ariel Lezen, Sanjay Tejraj Parmar, Cherry Kit-Fong Hin, Tony Joseph Szturm

JMIR Neurotech 2025;4:e67779

Machine Learning–Based Explainable Automated Nonlinear Computation Scoring System for Health Score and an Application for Prediction of Perioperative Stroke: Retrospective Study

Machine Learning–Based Explainable Automated Nonlinear Computation Scoring System for Health Score and an Application for Prediction of Perioperative Stroke: Retrospective Study

In addition, we applied the EACH score to predict perioperative stroke to assess its performance in real-world clinical practice and examined its performance compared with traditional scores and other ML-based scoring systems. Perioperative stroke significantly impacts postoperative morbidity and mortality.

Mi-Young Oh, Hee-Soo Kim, Young Mi Jung, Hyung-Chul Lee, Seung-Bo Lee, Seung Mi Lee

J Med Internet Res 2025;27:e58021

Asynchronous Distance Learning Performance and Knowledge Retention of the National Institutes of Health Stroke Scale Among Health Care Professionals Using Video or e-Learning: Web-based Randomized Controlled Trial

Asynchronous Distance Learning Performance and Knowledge Retention of the National Institutes of Health Stroke Scale Among Health Care Professionals Using Video or e-Learning: Web-based Randomized Controlled Trial

Despite the decline in stroke incidence and mortality since 1990, the absolute number of stroke cases are increasing due to the steep growth in the global population, along with an aging demographic and a greater burden of risk factors across many parts of the world [1]. Hence, stroke remains a major public health issue due to its high morbidity rates [2]. Acute reperfusion therapies, such as intravenous thrombolysis and thrombectomy, improve functional and survival prognosis after stroke [3,4].

Avinash Koka, Loric Stuby, Emmanuel Carrera, Ahmed Gabr, Margaret O'Connor, Nathalie Missilier Peruzzo, Olivier Waeterloot, Friedrich Medlin, Fabien Rigolet, Thomas Schmutz, Patrik Michel, Thibaut Desmettre, Mélanie Suppan, Laurent Suppan

J Med Internet Res 2025;27:e63136

Poststroke eHealth Technologies–Based Rehabilitation for Upper Limb Recovery: Systematic Review

Poststroke eHealth Technologies–Based Rehabilitation for Upper Limb Recovery: Systematic Review

Home-based TR allows to meet the rehabilitation needs of stroke survivors living in rural areas with limited health services, especially in westernized countries, where the stroke burden is rapidly increasing [22]. Home-based TR implies access at any time and from any place to rehabilitation services to address stroke aspects: (1) motor function: upper and lower extremities, balance, and gait; (2) cognitive function: spatial neglect, cognition, and memory; and (3) language: aphasia [23].

Margherita Rampioni, Sara Leonzi, Luca Antognoli, Anna Mura, Vera Stara

J Med Internet Res 2025;27:e57957

Assessment of the Sensitivity of a Smartphone App to Assist Patients in the Identification of Stroke and Myocardial Infarction: Cross-Sectional Study

Assessment of the Sensitivity of a Smartphone App to Assist Patients in the Identification of Stroke and Myocardial Infarction: Cross-Sectional Study

In the first of a series of validation steps, this study evaluated the sensitivity and usability of ECHAS in appropriately triaging patients who have already sought care in the ED for symptoms of a possible stroke, MI, or related conditions. ECHAS (Emergency Call for Heart Attack and Stroke) flowchart of “history and examination” functions for symptoms concerning cardiac or stroke emergencies.

Amar Dhand, Rama Mangipudi, Anubodh S Varshney, Jonathan R Crowe, Andria L Ford, Nancy K Sweitzer, Min Shin, Samuel Tate, Haissam Haddad, Michael E Kelly, James Muller, Jay S Shavadia

JMIR Form Res 2025;9:e60465

Stroke Diagnosis and Prediction Tool Using ChatGLM: Development and Validation Study

Stroke Diagnosis and Prediction Tool Using ChatGLM: Development and Validation Study

Stroke ranks among the leading causes of morbidity and mortality worldwide. The overall burden of stroke, in terms of the absolute number of individuals affected or left disabled by the condition, has been increasing, particularly in China [1-3]. There are significant disparities in stroke incidence, prevalence, acute care, rehabilitation, risk factor management, and outcomes [4].

Xiaowei Song, Jiayi Wang, Feifei He, Wei Yin, Weizhi Ma, Jian Wu

J Med Internet Res 2025;27:e67010