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Investigation of Study Procedures to Estimate Sensitivity and Reliability of a Virtual Physical Assessment Developed for Workplace Concussions: Method-Comparison Feasibility Study

Investigation of Study Procedures to Estimate Sensitivity and Reliability of a Virtual Physical Assessment Developed for Workplace Concussions: Method-Comparison Feasibility Study

People living with acquired brain injuries (ABIs) or concussions were recruited from ABI outpatient clinics publicly funded or Worker Safety and Insurance Board (WSIB) clinics based out of the Ottawa Hospital Rehabilitation Centre (TOHRC). Inpatients from the TOHRC ABI inpatient rehabilitation service were also recruited.

Keely Barnes, Heidi Sveistrup, Mark Bayley, Mary Egan, Martin Bilodeau, Michel Rathbone, Monica Taljaard, Motahareh Karimijashni, Shawn Marshall

JMIR Neurotech 2024;3:e57661

Development of a System for Predicting Hospitalization Time for Patients With Traumatic Brain Injury Based on Machine Learning Algorithms: User-Centered Design Case Study

Development of a System for Predicting Hospitalization Time for Patients With Traumatic Brain Injury Based on Machine Learning Algorithms: User-Centered Design Case Study

Traumatic brain injury (TBI) surgery increases the risk of certain complications, posttraumatic head injury complications that can lead to severe acute and chronic morbidity and mortality, and these complications are known risk factors for prolonged hospital stays [1-4].

Huan Zhou, Cheng Fang, Yifeng Pan

JMIR Hum Factors 2024;11:e62866

An App for Navigating Patient Transportation and Acute Stroke Care in Northwestern Ontario Using Machine Learning: Retrospective Study

An App for Navigating Patient Transportation and Acute Stroke Care in Northwestern Ontario Using Machine Learning: Retrospective Study

It is estimated that for every minute of delay in treating an acute ischemic stroke, 1.9 million brain cells die, 13.8 billion synapses are damaged, and 12 kilometers of axonal fibers are lost [1]. Patients eligible for time-sensitive therapies should be transported to the closest hospital capable of providing services for the diagnosis and treatment of stroke [5]. Patients accessing care for stroke in Northwestern Ontario (NWO), Canada, have particular challenges.

Ayman Hassan, Rachid Benlamri, Trina Diner, Keli Cristofaro, Lucas Dillistone, Hajar Khallouki, Mahvareh Ahghari, Shalyn Littlefield, Rabail Siddiqui, Russell MacDonald, David W Savage

JMIR Form Res 2024;8:e54009

Efficacy of Digital Dance on Brain Imagery, Cognition, and Health: Randomized Controlled Trial

Efficacy of Digital Dance on Brain Imagery, Cognition, and Health: Randomized Controlled Trial

However, no studies have evaluated the impact of digital somatosensory dance games with an explicit focus on brain signatures and healthy aging. Hence, this randomized controlled trial (RCT) aimed to study hypothetical benefits of digital somatosensory dance games on structural and functional brain imaging findings, cognitive performance, physical health, and mental health biomarkers.

Heng-Hsin Tung, Chen-Yuan Kuo, Pei-Lin Lee, Chih-Wen Chang, Kun-Hsien Chou, Ching-Po Lin, Liang-Kung Chen

J Med Internet Res 2024;26:e57694

Invasive Brain-Computer Interfaces: A Critical Assessment of Current Developments and Future Prospects

Invasive Brain-Computer Interfaces: A Critical Assessment of Current Developments and Future Prospects

Invasive brain-computer interfaces (BCIs) have recently attracted significant attention due to their potential to revolutionize the interaction between humans and machines. By directly interfacing with the brain, these devices offer profound implications for medical therapies and augmentative technologies. This viewpoint discusses the latest advancements, evaluates the benefits against the potential risks, and considers the ethical and regulatory landscapes shaping the future of invasive BCIs.

Pieter Kubben

JMIR Neurotech 2024;3:e60151

Smartphone Pupillometry and Machine Learning for Detection of Acute Mild Traumatic Brain Injury: Cohort Study

Smartphone Pupillometry and Machine Learning for Detection of Acute Mild Traumatic Brain Injury: Cohort Study

The pupillary light reflex (PLR) is a biomarker of neurological disease demonstrated by the reaction of the pupil to a light stimulus [1] that is commonly used in the management of moderate to severe traumatic brain injury (TBI) [2,3]. The pupil has both sympathetic and parasympathetic innervation that can be affected by mild TBI (m TBI).

Anthony J Maxin, Do H Lim, Sophie Kush, Jack Carpenter, Rami Shaibani, Bernice G Gulek, Kimberly G Harmon, Alex Mariakakis, Lynn B McGrath, Michael R Levitt

JMIR Neurotech 2024;3:e58398

The Effectiveness of a Digital App for Reduction of Clinical Symptoms in Individuals With Panic Disorder: Randomized Controlled Trial

The Effectiveness of a Digital App for Reduction of Clinical Symptoms in Individuals With Panic Disorder: Randomized Controlled Trial

As brain imaging technology advances, a great deal of functional mapping information on the human brain has been accumulated from positron emission tomography (PET), functional magnetic resonance imaging (f MRI), and functional near-infrared spectroscopy (f NIRS). Among these technologies, f NIRS can measure brain activity in a noninvasive and safe manner through measuring changes in the hemoglobin oxygenation state of the human brain [15].

KunJung Kim, Hyunchan Hwang, Sujin Bae, Sun Mi Kim, Doug Hyun Han

J Med Internet Res 2024;26:e51428

Cerebral Mechanism of Tuina on the Descending Pain Inhibitory System in Knee Osteoarthritis: Protocol for a Randomized Controlled Trial

Cerebral Mechanism of Tuina on the Descending Pain Inhibitory System in Knee Osteoarthritis: Protocol for a Randomized Controlled Trial

Moreover, the subcortical structures and multiple cortices of the brain, comprising the anterior cingulate cortex, amygdala, insula, and hypothalamus, are also involved in pain modulation via the descending pain inhibitory system. The function of the descending pain inhibitory system in pain modulation and the management of the same have been substantially referenced [14,15].

Hui Xu, Zheng Wang, Zhen Wang, Hang Zhou, Juan Guo, Wanyu Li, Yunfeng Zhou

JMIR Res Protoc 2024;13:e52820