Games for Pain Management

Extended Reality (XR) in Pediatric Acute and Chronic Pain: Systematic Review and Evidence Gap Map

Courtney W Hess, Brittany N Rosenbloom, Giulia Mesaroli, Cristal Lopez, Nhat Ngo, Estreya Cohen, Carley Ouellette, Jeffrey I Gold, Deirdre Logan, Laura E Simons, Jennifer N Stinson

JMIR Pediatr Parent 2025 (Apr 07); 8:e63854

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Cooperative Virtual Reality Gaming for Anxiety and Pain Reduction in Pediatric Patients and Their Caregivers During Painful Medical Procedures: Protocol for a Randomized Controlled Trial

Stefan Liszio, Franziska Bäuerlein, Jens Hildebrand, Carolin van Nahl, Maic Masuch, Oliver Basu

JMIR Res Protoc 2025 (Mar 31); 14:e63098

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At-Home Virtual Reality Intervention for Patients With Chronic Musculoskeletal Pain: Single-Case Experimental Design Study

Syl Slatman, Lieke Heesink, Reinoud Achterkamp, José Broeks, Nelson Monteiro de Oliveira, Remko ter Riet, Marjolein Stegeman, Monique Tabak

JMIR XR Spatial Comput 2025 (Mar 04); 2:e58784

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Virtual Reality Interventions and Chronic Pain: Scoping Review

Michael E Ding, Hajar Traiba, Hector R Perez

J Med Internet Res 2025 (Feb 18); 27:e59922

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Exploring the Effect of an 8-Week AI-Composed Exercise Program on Pain Intensity and Well-Being in Patients With Spinal Pain: Retrospective Cohort Analysis

Annika Griefahn, Florian Avermann, Christoff Zalpour, Robert Percy Marshall, Inés Cordon Morillas, Kerstin Luedtke

JMIR Form Res 2025 (Feb 18); 9:e57826

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Gamified Web-Delivered Attentional Bias Modification Training for Adults With Chronic Pain: Randomized, Double-Blind, Placebo-Controlled Trial

Julie F Vermeir, Melanie J White, Daniel Johnson, Geert Crombez, Dimitri M L Van Ryckeghem

JMIR Serious Games 2025 (Jan 16); 13:e50635

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Virtual Reality–Applied Home-Visit Rehabilitation for Patients With Chronic Pain: Protocol for Single-Arm Pre-Post Comparison Study

Hiroki Funao, Ryo Momosaki, Mayumi Tsujikawa, Eiji Kawamoto, Ryo Esumi, Motomu Shimaoka

JMIR Res Protoc 2024 (Dec 30); 13:e58734

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Evaluation of a New Mobile Virtual Reality Setup to Alter Pain Perception: Pilot Development and Usability Study in Healthy Participants

Samuel E J Knobel, Raphael Oberson, Jonas Räber, Narayan Schütz, Niklaus Egloff, Angela Botros, Stephan M Gerber, Tobias Nef, Lukas Heydrich

JMIR Serious Games 2024 (Dec 11); 12:e52340

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Using Digital Art and Attachment Priming in a Web-Based Serious Game to Reduce Pain and Social Disconnection in Individuals With Chronic Pain and Loneliness: Randomized Controlled Trial

Jorge Peña, Ian Koebner, William Weisman

JMIR Serious Games 2024 (Nov 27); 12:e52294

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Game-Based eHealth Interventions for the Reduction of Fatigue in People With Chronic Diseases: Systematic Review and Meta-Analysis

Leonie S Warlo, Souraya El Bardai, Andrica de Vries, Marie-Lise van Veelen, Suzan Moors, Edmond HHM Rings, Jeroen S Legerstee, Bram Dierckx

JMIR Serious Games 2024 (Oct 17); 12:e55034

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Implementation of a Virtual Reality Intervention in Outpatient Physiotherapy for Chronic Pain: Protocol for a Pilot Implementation Study

Alexander Elser, Christian Kopkow, Axel Georg Schäfer

JMIR Res Protoc 2024 (Sep 23); 13:e58089

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Use of Biofeedback-Based Virtual Reality in Pediatric Perioperative and Postoperative Settings: Observational Study

Zandantsetseg Orgil, Anitra Karthic, Nora F Bell, Lisa M Heisterberg, Sara E Williams, Lili Ding, Susmita Kashikar-Zuck, Christopher D King, Vanessa A Olbrecht

JMIR Perioper Med 2024 (Sep 16); 7:e48959

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Immersive and Nonimmersive Virtual Reality–Assisted Active Training in Chronic Musculoskeletal Pain: Systematic Review and Meta-Analysis

Hermione Hin Man Lo, Mengting Zhu, Zihui Zou, Cho Lee Wong, Suzanne Hoi Shan Lo, Vincent Chi-Ho Chung, Samuel Yeung-Shan Wong, Regina Wing Shan Sit

J Med Internet Res 2024 (Aug 19); 26:e48787

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Exploring Relations Between Unique Patient Characteristics and Virtual Reality Immersion Level on Anxiety and Pain in Patients Undergoing Venipuncture: Secondary Analysis of a Randomized Control Trial

Jeffrey I Gold, Krystal M Akbar, Sandra Avila, Nhat H Ngo, Margaret J Klein

J Med Internet Res 2024 (Jul 01); 26:e53196

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Effects of Virtual Reality Therapy Combined With Conventional Rehabilitation on Pain, Kinematic Function, and Disability in Patients With Chronic Neck Pain: Randomized Controlled Trial

Qifan Guo, Liming Zhang, Leo Lianyi Han, Chenfan Gui, Guanghui Chen, Chunyan Ling, Wei Wang, Qiang Gao

JMIR Serious Games 2024 (Apr 24); 12:e42829

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Virtual Reality Therapy for the Management of Chronic Spinal Pain: Systematic Review and Meta-Analysis

Tongtong Zhang, Xin Li, Xuan Zhou, Lixia Zhan, Fan Wu, Zefan Huang, Yuxun Sun, Yufei Feng, Qing Du

JMIR Serious Games 2024 (Feb 12); 12:e50089

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Global Scientific Trends in Virtual Reality for Pain Treatment From 2000 to 2022: Bibliometric Analysis

Xun Yang, Sen Zhong, Sheng Yang, Meng He, Xu Xu, Shisheng He, Guoxin Fan, Lijun Liu

JMIR Serious Games 2023 (Nov 14); 11:e48354

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Use of Virtual Reality in Interdisciplinary Multimodal Pain Treatment With Insights From Health Care Professionals and Patients: Action Research Study

Darcy Ummels, Elise Cnockaert, Inge Timmers, Marlies den Hollander, Rob Smeets

JMIR Rehabil Assist Technol 2023 (Nov 10); 10:e47541

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Virtual Reality for Chronic Pain Management Among Historically Marginalized Populations: Systematic Review of Usability Studies

Marika Dy, Kristan Olazo, Sarah Lisker, Ellenor Brown, Anindita Saha, Jessica Weinberg, Urmimala Sarkar

J Med Internet Res 2023 (Jun 06); 25:e40044

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Effects of Exergaming on Musculoskeletal Pain in Older Adults: Systematic Review and Meta-analysis

Nan Mo, Jin yu Feng, Hai xia Liu, Xiao yu Chen, Hui Zhang, Hui Zeng

JMIR Serious Games 2023 (Apr 25); 11:e42944

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