Published on in Vol 7, No 2 (2019): Apr-Jun

Preprints (earlier versions) of this paper are available at, first published .
A Web-Based Serious Game for Health to Reduce Perioperative Anxiety and Pain in Children (CliniPup): Pilot Randomized Controlled Trial

A Web-Based Serious Game for Health to Reduce Perioperative Anxiety and Pain in Children (CliniPup): Pilot Randomized Controlled Trial

A Web-Based Serious Game for Health to Reduce Perioperative Anxiety and Pain in Children (CliniPup): Pilot Randomized Controlled Trial


  1. Bray L, Sharpe A, Gichuru P, Fortune P, Blake L, Appleton V. The Acceptability and Impact of the Xploro Digital Therapeutic Platform to Inform and Prepare Children for Planned Procedures in a Hospital: Before and After Evaluation Study. Journal of Medical Internet Research 2020;22(8):e17367 View
  2. Floryan M, Chow P, Schueller S, Ritterband L. The Model of Gamification Principles for Digital Health Interventions: Evaluation of Validity and Potential Utility. Journal of Medical Internet Research 2020;22(6):e16506 View
  3. Suppan M, Gartner B, Golay E, Stuby L, White M, Cottet P, Abbas M, Iten A, Harbarth S, Suppan L. Teaching Adequate Prehospital Use of Personal Protective Equipment During the COVID-19 Pandemic: Development of a Gamified e-Learning Module. JMIR Serious Games 2020;8(2):e20173 View
  4. Reeves K, O’Hare K, Shade L, Ludden T, McWilliams A, Manning M, Hogg M, Reynolds S, Shea C, Burton E, Calvert M, Derkowski D, Tapp H. Evaluation of a shared decision-making intervention for pediatric patients with asthma in the emergency department. Implementation Science Communications 2020;1(1) View
  5. Vass C, Davison N, Vander Stichele G, Payne K. A Picture is Worth a Thousand Words: The Role of Survey Training Materials in Stated-Preference Studies. The Patient - Patient-Centered Outcomes Research 2020;13(2):163 View
  6. Matthyssens L, Vanhulle A, Seldenslach L, Vander Stichele G, Coppens M, Van Hoecke E. A pilot study of the effectiveness of a serious game CliniPup® on perioperative anxiety and pain in children. Journal of Pediatric Surgery 2020;55(2):304 View
  7. Rantala A, Jansson M, Helve O, Lahdenne P, Pikkarainen M, Pölkki T. Parental Experiences of the Pediatric Day Surgery Pathway and the Needs for a Digital Gaming Solution: Qualitative Study. JMIR Medical Informatics 2020;8(11):e23626 View
  8. Yeung S, Irwin M, Cheung C. Environmental Enrichment in Postoperative Pain and Surgical Care. Annals of Surgery 2021;273(1):86 View
  9. Fucà E, Costanzo F, Bonutto D, Moretti A, Fini A, Ferraiuolo A, Vicari S, Tozzi A. Mobile-Health Technologies for a Child Neuropsychiatry Service: Development and Usability of the Assioma Digital Platform. International Journal of Environmental Research and Public Health 2021;18(5):2758 View
  10. Sajeev M, Kelada L, Yahya Nur A, Wakefield C, Wewege M, Karpelowsky J, Akimana B, Darlington A, Signorelli C. Interactive video games to reduce paediatric procedural pain and anxiety: a systematic review and meta-analysis. British Journal of Anaesthesia 2021;127(4):608 View
  11. Mathias E, Pai M, Guddattu V, Bramhagen A. Non-pharmacological interventions to reduce anxiety among children undergoing surgery: A systematic review. Journal of Child Health Care 2023;27(3):466 View
  12. Mathias E, Pai M. Anxiety and Pain in Children Undergoing Surgery: A Scoping Review. Journal of PeriAnesthesia Nursing 2022;37(4):545 View
  13. Sarasmita M, Larasanty L, Kuo L, Cheng K, Chen H. A Computer-Based Interactive Narrative and a Serious Game for Children With Asthma: Development and Content Validity Analysis. Journal of Medical Internet Research 2021;23(9):e28796 View
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  15. Warsinsky S, Schmidt-Kraepelin M, Rank S, Thiebes S, Sunyaev A. Conceptual Ambiguity Surrounding Gamification and Serious Games in Health Care: Literature Review and Development of Game-Based Intervention Reporting Guidelines (GAMING). Journal of Medical Internet Research 2021;23(9):e30390 View
  16. Mathias E, Pai M, Bramhagen A. Effect of Distraction Interventions on Anxiety in Children Undergoing Surgery: A Meta-Analysis. Journal of Health and Allied Sciences NU 2023;13(03):323 View
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Books/Policy Documents

  1. Perasso G. Handbook of Research on Play Specialism Strategies to Prevent Pediatric Hospitalization Trauma. View