Awareness, Prevention, Detection, and Therapy Applications for Depression and Anxiety in Serious Games for Children and Adolescents: Systematic Review

Journals

1. Martinez K, Menéndez-Menéndez M, Bustillo A. A New Measure for Serious Games Evaluation: Gaming Educational Balanced (GEB) Model. Applied Sciences 2022;12(22):11757 View
2. Damaševičius R, Maskeliūnas R, Blažauskas T. Serious Games and Gamification in Healthcare: A Meta-Review. Information 2023;14(2):105 View
3. Wang Y, Wang Z, Liu G, Wang Z, Wang Q, Yan Y, Wang J, Zhu Y, Gao W, Kan X, Zhang Z, Jia L, Pang X. Application of Serious Games in Health Care: Scoping Review and Bibliometric Analysis. Frontiers in Public Health 2022;10 View
4. Kim Y, Hong S, Choi M. Effects of Serious Games on Depression in Older Adults: Systematic Review and Meta-analysis of Randomized Controlled Trials. Journal of Medical Internet Research 2022;24(9):e37753 View
5. Rickard N, Kurt P, Meade T. Systematic assessment of the quality and integrity of popular mental health smartphone apps using the American Psychiatric Association's app evaluation model. Frontiers in Digital Health 2022;4 View
6. Serrano-Mamolar A, Miguel-Alonso I, Checa D, Pardo-Aguilar C. Towards learner performance evaluation in iVR learning environments using eye-tracking and Machine-learning. Comunicar 2023;31(76) View
7. Klimczyk P. What is the post-game depression? A narrative inquiry. Cyberpsychology: Journal of Psychosocial Research on Cyberspace 2023;17(2) View
8. Barcena-Vazquez J, Caro K, Bermudez K, Zatarain-Aceves H. Designing and evaluating Reto Global, a serious video game for supporting global warming awareness. International Journal of Human-Computer Studies 2023;177:103080 View
9. David O, Fodor L. Preventing mental illness in children that experienced maltreatment the efficacy of REThink online therapeutic game. npj Digital Medicine 2023;6(1) View
10. Sosa-Espadas C, Orozco-del-Castillo M, Cuevas-Cuevas N, Recio-Garcia J. IREX: Iterative Refinement and Explanation of classification models for tabular datasets. SoftwareX 2023;23:101420 View
11. Martinez K, Checa D, Bustillo A. Development of the Engagement Playability and User eXperience (EPUX) Metric for 2D-Screen and VR Serious Games: A Case-Study Validation of Hellblade: Senua’s Sacrifice. Electronics 2024;13(2):281 View
12. Veerman L, Fjermestad K, Vatne T, Sterkenburg P, Derks S, Brouwer-van Dijken A, Willemen A. Cultural applicability and desirability of ‘Broodles’: The first serious game intervention for siblings of children with disabilities. PEC Innovation 2024;4:100277 View
13. Rodriguez-Garcia B, Guillen-Sanz H, Checa D, Bustillo A. A systematic review of virtual 3D reconstructions of Cultural Heritage in immersive Virtual Reality. Multimedia Tools and Applications 2024;83(42):89743 View
14. Gómez-Cambronero Á, Mann A, Mira A, Doherty G, Casteleyn S. Smartphone-based serious games for mental health: a scoping review. Multimedia Tools and Applications 2024;83(36):84047 View
15. Khodakarami F, Sekhavat Y, Alizadeh F. Evergreen: An existential video game to increase the indices associated with existential thinking in the audience. Entertainment Computing 2024;50:100679 View
16. Omylinska-Thurston J, Aithal S, Liverpool S, Clark R, Moula Z, Wood J, Viliardos L, Rodríguez-Dorans E, Farish-Edwards F, Parsons A, Eisenstadt M, Bull M, Dubrow-Marshall L, Thurston S, Karkou V. Digital Psychotherapies for Adults Experiencing Depressive Symptoms: Systematic Review and Meta-Analysis. JMIR Mental Health 2024;11:e55500 View
17. Livanou M, Manitsa I, Hulusic V, Samara M, Bull M, De Caro A. The development of ReGoal, a serious mobile game for young people with conduct problems*. Behaviour & Information Technology 2025;44(11):2670 View
18. Catalan C, Gega L, Hook J. Storytelling Games for General Anxiety: Clinician Perspectives on Walking Simulator Games as Intervention. Proceedings of the ACM on Human-Computer Interaction 2024;8(CHI PLAY):1 View
19. Stasolla F, Curcio E, Passaro A, Di Gioia M, Zullo A, Martini E. Exploring the Combination of Serious Games, Social Interactions, and Virtual Reality in Adolescents with ASD: A Scoping Review. Technologies 2025;13(2):76 View
20. Burguera-Bernalte D, Gil-Gómez J, Redolat R, Mesa-Gresa P. NeuroApp, serious games for enhancing neuroscience learning in undergraduate students: A pilot study. Entertainment Computing 2025;54:100943 View
21. Silva L, Santos M, Silva K, Seixas B, Chiacchio F, Chiacchio A. Analysis of The Feasibility of Digital Therapeutic Interventions in the Treatment of Anxiety in Young People: An Integrative Literature Review. Revista de Gestão Social e Ambiental 2025;19(4):e011980 View
22. Tiburcio M, Martínez-Vélez N, Bernal-Pérez R, Huss J, Eichenberg C. Exploring Mexican psychotherapist's attitudes towards knowledge and use of serious games in clinical practice. Frontiers in Digital Health 2025;7 View
23. Alweis E, Alweis R. A Narrative Review of the Benefits of Board Games in Health. Cureus 2025 View
24. Wijaya A, Gunawan D, Leonardo R, Ramdhan D. “Abysssense” : The Impact of Serious Games on Awareness of Thalassophobia. Procedia Computer Science 2025;269:608 View

Books/Policy Documents

1. Gatto C, Martinez K, De Paolis L. Extended Reality. View
2. Zeffiro V, Di Fuccio R, Mazzotta R, Ronni A, Alvaro R, Bulfone G, D’Agostino F. Methodologies and Intelligent Systems for Technology Enhanced Learning, Workshops, 12th International Conference. View
3. Martinez K, Checa D. Extended Reality. View
4. Madera-Torres I, Orozco-del-Castillo M, Moreno-Cimé S, Bermejo-Sabbagh C, Cuevas-Cuevas N. Telematics and Computing. View
5. Al-Mahayri Z, Nagy M. Raising Genomics Literacy, Knowledge, and Awareness. View
6. Vallefuoco E, Ponticelli E, Gison G, Pepino A. Extended Reality. View

Conference Proceedings

1. Floreste T, Yasui A, Brandão A, Vittori K, Pereira L, de Souza Santos F, Gama S. 2023 IEEE 11th International Conference on Serious Games and Applications for Health (SeGAH). SANE – A Journey for Health: Prototype Game Design and a Cognitive Walkthrough Evaluation View
2. Elyasi S, Nezhad A, Taghiyareh F. 2023 14th International Conference on Information and Knowledge Technology (IKT). Exploring the Relationship Between Gameplay Log Data and Depression & Anxiety View
3. Muniandy N, Kamsin A, Sabri M. 2023 9th International HCI and UX Conference in Indonesia (CHIuXiD). Enhancing Children's Health Awareness through Narrative Game-Based Learning using Digital Technology: A Framework and Methodology View
4. Ooms S. Adjunct Proceedings of the 32nd ACM Conference on User Modeling, Adaptation and Personalization. Promoting Mental Health of Adolescents with a Mild Intellectual Disability View
5. Bjørner T, Andersen S, Sommer E, Andersen K, Qvarnstrøm M, Enevoldsen M, Larsson N, Sørensen S. Proceedings of the 2024 International Conference on Information Technology for Social Good. A Serious Game for Promoting Knowledge about Suicidal Thoughts for Students at Higher Education View
6. Leung G, Cook B, Daniel-Watanabe L, Subramaniam N, Finnemann J, Woolley T, Powell C, Sitnikov S, Fletcher P. 2025 IEEE Conference on Serious Games and Applications for Health (SeGAH). Game-Based Biofeedback Increases Subjective Ratings of Interoceptive Awareness View
7. Curcio E, Stasolla F, Zullo A, Gioia M, Passaro A. Position Papers of the 20th Conference on Computer Science and Intelligence Systems. Enhancing Socio-Emotional Skills in Children with Autism through AI-Powered Serious Games: A Narrative Review View