Serious Games for Health and Medicine

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Articles published in 2026 in this theme: 94 (scroll down to load remaining articles)

2026

People exercising on red mats with sensors in a gym

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The Effect of Integrated Aerobic and Cognitive Training (Activ4Brain) on Cognition and Neurophysiology in Older Adults: Protocol for a Controlled Trial

Hicran Besikci, Kaan Akalp, Luís Rama, Beatriz Branquinho Gomes, José Pedro Leitão Ferreira, Susana Mouga, Inês Bernardino, Miguel Castelo-Branco, Ana Rita Sousa e Silva, Ana Maria Teixeira, Maria José Ribeiro

JMIR Res Protoc 2026 (Sep 17); 15:e92631

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Elderly Asian man using a tablet by a window

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Scenario-Based Serious Game for Screening Mild Cognitive Impairment in Older Adults: Cross-Sectional Preliminary Validation Study

Bomyi Jeon, Chi Hyeon Noh, Soo Rim Noh, Seung Bin Cho, Yerin Shim, Sungkun Cho

JMIR Serious Games 2026 (Sep 16); 14:e92334

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Woman wearing VR headset outdoors, reaching with hands

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Bringing the Green Environment From Outdoors to Indoors Through Virtual Reality for Psychological Well-Being: Quasi-Experimental Study

Dorothy Bai, Jou-Ting Lin, Hao-Yun Huang, Hsin-Yen Yen

J Med Internet Res 2026 (Sep 16); 28:e93494

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Elderly man wearing VR headset and controllers, playing a virtual reality game.

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Dynamic Adoption of Immersive Tai Chi Training Among Older Adults: Exploratory Qualitative-Dominant Longitudinal Mixed Methods Follow-Up Study of Virtual and Mixed Reality Delivery

Xiacheng Song, Huafeng Qu, Jing Jin, Lu Sun, Xiqiong Yi, Junfeng Zhu, Huirong Huang

JMIR Serious Games 2026 (Sep 15); 14:e96262

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Man with walker at bus stop with modern urban backdrop

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Development of a Mixed-Reality Application for Volitional Step Training in People With Multiple Sclerosis: Cross-Sectional Qualitative User-Centered Co-Design Study

Gabriele Perachiotti, Isolde Martina Busch, Ersilia Vallefuoco, Giovanni D'Errico, Nicola Moccaldi, Sofia Straudi, Pasquale Arpaia

JMIR Serious Games 2026 (Sep 14); 14:e94312

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Children playing a board game with animal pieces and cards

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Collaborative Gameplay for Children’s Self-Efficacy in Computational Thinking: Qualitative Cross-Sectional Design Science Research Case Study

Valéria Moreira Pinto, Licinio Roque, Mariana Seiça

JMIR Serious Games 2026 (Sep 09); 14:e94416

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Children learning computer skills in a classroom with laptops and a projector.

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Gamified Adult Basic Life Support Training for Schoolchildren Using Minecraft Education Edition: Cross-Sectional Program Evaluation

Manuel Pardo Rios, Vanessa Fois González, Ana Belén Ocampo Cervantes, Carmen Amalia López López, José Tortosa Alcázar, Miriam Mendoza López, Petronila Mireia Alcázar Artero, Daniel Guillén Martínez, Robert Greif, Nino Fijačko, Aida Carballo-Fazanes, Cristian Abelairas-Gómez

JMIR Serious Games 2026 (Sep 09); 14:e93141

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Young boy wearing a VR headset and holding controllers, playing a video game at home.

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Gamified Virtual Reality Training for Pneumatic Reduction of Intussusception in Children: Formative Evaluation of a Low-Fidelity Prototype

Ahmad Nizamuddin bin Jipli, Ahmad M S Elaklouk, Anas Shikha, Ibrahim Edris

JMIR Form Res 2026 (Sep 08); 10:e83661

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Elderly couple enjoying virtual reality with a VR headset and cane

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Electroencephalography Functional Network Responses to Immersive Virtual Reality in Alzheimer Disease and Mild Cognitive Impairment: Exploratory Single-Session 3-Group Repeated-Measures Study

Yi Hao Yao, SHIBO XU, Eun-Seong Kim, Eun-Ah Kim, Yan-Xiong Wang, Hyun Soo Kim, Do Hoon Kim, Jun-Ge Liang, Young-Kee Shin, Nam-Young Kim

JMIR Serious Games 2026 (Sep 04); 14:e95160

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Tablet displaying HIV testing app, with self-test kit and graph showing increased testing uptake.

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Efficacy of an Interactive Life Simulation Gaming App on Improving HIV Testing Uptake Among Adolescents and Young Adults at Risk for HIV: Results of a Randomized Controlled Trial

Amanda D Castel, Irene Kuo, Adam Ciarleglio, Lucas Kauzlarich, Constance Trexler, Sachi Banerji, Tamara C Moscovich, John C Banas, Constanza Carney, Callen Shaw, Daniel Greenberg

JMIR Serious Games 2026 (Sep 04); 14:e82297

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Child with headphones lying in bed, looking at a smartphone

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The Preliminary Efficacy and Feasibility of SMILE Serious Game for Adolescents and Young Adults: Protocol for Cluster Randomized Multisite Adaptive Trial Design

Ewelina Smoktunowicz, Jan Maciejewski, Magdalena Lesnierowska, Magdalena Pietrzak, Franziska Großwendt, Gwendolyn Mayer, Jobst-Hendrik Schultz, Nelli Tschobur, Mel McKendrick, Helen Stocks, Francesca Floris, Dina Guglielmi, Zouhair Haddi, Carlo Mazzola, Izidor Mlakar, Urška Smrke, Laura Fernández García, Esther Parra Vidales, Elisa Sáez Muñoz, Sebastian Bruchhaus, Matthias Hemmje, Dominic Heutelbeck, Dah Diarra, Habib Nasser, Alex Butean, Marco Polak, Panagiota Mourettou, Angelos Parmatzias, Ula Kolinska, Matthias Schwannauer

JMIR Res Protoc 2026 (Sep 03); 15:e96292

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Gamer wearing headphones plays video game on computer monitor

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Associations in Both Directions Between Internet Gaming Disorder and Suicidal Ideation and Attempts Among Chinese Adolescent Gamers: Two-Wave Prospective Cohort Study

Pu Peng, Zhangming Chen, Silan Ren, Yudiao Liang, Youguo Tan, Xiaogang Chen, Jinsong Tang, Yanhui Liao

J Med Internet Res 2026 (Sep 02); 28:e86919

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Virtual reality hand selecting a red tomato from a grocery store produce display.

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Behavioral and Physiological Responses to Sensory and Cognitive Demands in an Immersive Virtual Reality Shopping Task in Unimpaired Young Adults: Within-Subjects Experimental Study

Salvatore Luca Cucinella, Job LA Mulder, Joost CF de Winter, Laura Marchal-Crespo

JMIR Serious Games 2026 (Aug 28); 14:e84893

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Young girl playing video games on a couch, looking excited

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Serious Game–Based Attention Assessment for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents: Preliminary Cross-Sectional Convergent Validation Study

Alejandro Panagiotidis-Arrizabalaga, Ana Lavalle, Miguel A Teruel, Javier Sanchis, Nicolás Ruiz-Robledillo, Borja Costa-López

JMIR Serious Games 2026 (Aug 28); 14:e80441

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Dentist explains 3D dental scan in VR headset to patient.

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Immersive Virtual Reality for Patient Education in Orthodontics: Cross-Sectional Feasibility and Acceptability Study

Yoo Jin Kim, Glenn Jou, Hyun Cho, Mathias Stephen Fallis, Glenn Sameshima

JMIR Serious Games 2026 (Aug 27); 14:e102686

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Man at computer with therapist taking notes in background.

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Executive Dysfunction—A Serious Game for Assessment in Real-Life Contexts: Development and Cross-Sectional Usability Study

Daniela Olivares, David Martínez-Pernía, Loreto Olavarría, Mauricio Cerda, Diego Montenegro, Cristian Ramírez, Rodrigo Nieto, Gonzalo Farías, Andrea Slachevsky

JMIR Serious Games 2026 (Aug 27); 14:e94860

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Young girl with cerebral palsy using a tablet in a specialized stroller outdoors

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Effects of Virtual Reality–Based Intervention Combined With Conventional Therapy on Upper-Limb Function in Children With Hemiplegic Cerebral Palsy: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Chengqian Feng, Yang Li, Letian Cheng, Baizhen Xiong, Zhicheng Lin, Caihua Huang

JMIR Serious Games 2026 (Aug 26); 14:e98694

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Elderly man plays Sonic the Hedgehog on a computer with adaptive gaming equipment.

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Active Video Gaming Intervention in Adults With Mobility Impairments: Concurrent Mixed Methods Single-Arm Pilot Study

Laurie A Malone, Christen J Mendonca, Sangeetha Mohanraj, Mohanraj Thirumalai

JMIR Serious Games 2026 (Aug 26); 14:e73764

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Man reviews care facility options on laptop, showing a meeting room and numbered list of choices.

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Web-Based Narrative Game Intervention for Initiating Advance Care Planning Among Adults: Exploratory Cross-Sectional Feasibility and Acceptability Study

Takashi Iwashiro

JMIR Form Res 2026 (Aug 24); 10:e94395

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Woman wearing VR headset relaxes on a blue couch, experiencing virtual reality

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Novel Virtual Reality Methods for the Treatment of Obsessive-Compulsive Disorder Using a User-Centered Design Approach: Focus Group Study

Michael Colman, Josie F A Millar, Bhagyashree Patil, Daniel J Finnegan, Mhairi Kristoffersen, Danae Stanton Fraser

JMIR XR Spatial Comput 2026 (Aug 20); 3:e92410

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