Game-Based eHealth Interventions for the Reduction of Fatigue in People With Chronic Diseases: Systematic Review and Meta-Analysis

Leonie S Warlo   ^{1, 2 *} , MSc ;   Souraya El Bardai   ^{1, 2 *} , MSc ;   Andrica de Vries   ^{2, 3 *} , MD, PhD ;   Marie-Lise van Veelen   ^{4 *} , MD, PhD ;   Suzan Moors   ^{5 *} , BSc ;   Edmond HHM Rings   ^{6 *} , MD, PhD ;   Jeroen S Legerstee   ^{1, 7, 8 *} , PhD ;   Bram Dierckx   ^{1 *} , MD, PhD

¹ Department of Child and Adolescent Psychiatry/Psychology, Sophia Children’s Hospital, Erasmus Medical Center, Rotterdam, Netherlands

² Department of Pediatric Oncology, Sophia Children’s Hospital, Erasmus Medical Center, Rotterdam, Netherlands

³ Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands

⁴ Department of Neurosurgery, Sophia Children's Hospital, Erasmus Medical Center, Rotterdam, Netherlands

⁵ Department of Physiotherapy, Sophia Children's Hospital, Erasmus Medical Center, Rotterdam, Netherlands

⁶ Department of Pediatrics, Sophia Children’s Hospital, Erasmus Medical Center, Rotterdam, Netherlands

⁷ Levvel, Academic Center for Child and Adolescent Psychiatry and Specialized Youth Care, Amsterdam, Netherlands

⁸ Research Institute of Child Development and Education, University of Amsterdam, Amsterdam, Netherlands

*all authors contributed equally